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| 05/08/2022 | 17:30 | Club León | - | Atlético San Luis | 2:0 (0:0) | |
| 06/08/2022 | 17:00 | Puebla FC | - | Deportivo Toluca | 0:3 (0:2) | |
| 17:00 | UANL Tigres | - | Mazatlán FC | 2:1 (1:1) | ||
| 17:15 | Deportivo Guadalajara | - | CF Monterrey | 0:1 (0:0) | ||
| 17:30 | Cruz Azul | - | Gallos Blancos | 2:1 (1:1) | ||
| 17:30 | Atlas Guadalajara | - | Santos Laguna | 2:2 (2:1) | ||
| 18:15 | FC Juárez | - | Pumas UNAM | 3:4 (3:2) | ||
| 18:45 | CF América | - | Club Necaxa | 1:0 (0:0) |
| » Tables | Home | Away | First round | Second round |
| 1 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 6 | 5 | 1 | 0 | 14:9 | 5 | 16 |
| 2 |
|
Deportivo Toluca | 6 | 4 | 2 | 0 | 13:6 | 7 | 14 |
| 3 |
|
Club Necaxa | 6 | 3 | 0 | 3 | 13:5 | 8 | 9 |
| 4 |
|
Cruz Azul | 6 | 3 | 0 | 3 | 13:13 | 0 | 9 |
| 5 |
|
Gallos Blancos | 7 | 2 | 2 | 3 | 11:9 | 2 | 8 |
| 6 |
|
CF Pachuca | 6 | 2 | 2 | 2 | 6:4 | 2 | 8 |
| 7 |
|
CF América | 6 | 2 | 1 | 3 | 10:12 | -2 | 7 |
| 8 |
|
Puebla FC | 6 | 2 | 0 | 4 | 9:14 | -5 | 6 |
| 9 |
|
FC Juárez | 7 | 1 | 0 | 6 | 10:27 | -17 | 3 |
| 2 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Tijuana | 6 | 5 | 1 | 0 | 17:3 | 14 | 16 |
| 2 |
|
Atlas Guadalajara | 7 | 4 | 3 | 0 | 21:7 | 14 | 15 |
| 3 |
|
CF Monterrey | 7 | 4 | 3 | 0 | 19:8 | 11 | 15 |
| 4 |
|
Deportivo Guadalajara | 6 | 3 | 0 | 3 | 6:8 | -2 | 9 |
| 5 |
|
Santos Laguna | 6 | 2 | 1 | 3 | 17:12 | 5 | 7 |
| 6 |
|
Club León | 6 | 2 | 1 | 3 | 8:7 | 1 | 7 |
| 7 |
|
UANL Tigres | 6 | 2 | 1 | 3 | 9:15 | -6 | 7 |
| 8 |
|
Atlético San Luis | 6 | 1 | 0 | 5 | 6:27 | -21 | 3 |
| 9 |
|
Mazatlán FC | 6 | 0 | 0 | 6 | 5:21 | -16 | 0 |
| Playoffs | |
| Playoffs |
