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| 1st(1st leg) | Dorados de Sinaloa | - | FC Juárez | 2:0 (2:0) | ||
| 2nd (2nd leg) | FC Juárez | - | Dorados de Sinaloa | 1:0 (1:0) | ||
| 1st(1st leg): 22/11/2018 03:00 | 2nd (2nd leg): 25/11/2018 01:00 | Winner: Dorados de Sinaloa | ||||
| 1st(1st leg) | Atlético San Luis | - | Atlante | 3:0 (2:0) | ||
| 2nd (2nd leg) | Atlante | - | Atlético San Luis | 2:0 (1:0) | ||
| 1st(1st leg): 23/11/2018 02:00 | 2nd (2nd leg): 26/11/2018 01:00 | Winner: Atlético San Luis | ||||
