 |
 |
|
|
| 19/10/2021 | 23:00 | CF Monterrey II | - | Leones Negros | 0:1 (0:0) | |
| 20/10/2021 | 01:05 | Venados FC | - | Mineros de Zacatecas | 3:1 (1:1) | |
| 03:05 | Pumas Tabasco | - | Cancún FC | 0:0 (0:0) | ||
| 23:00 | Club Celaya | - | Alebrijes de Oaxaca | 1:0 (0:0) | ||
| 21/10/2021 | 01:05 | TM Fútbol Club | - | Atlante | 1:1 (0:1) | |
| 03:05 | Cimarrones de Sonora | - | Coyotes de Tlaxcala | 3:0 (1:0) | ||
| 23:00 | Tapatío | - | Dorados de Sinaloa | 1:3 (0:1) | ||
| 24/10/2021 | 23:00 | Atlético Morelia | - | Tepatitlán | 2:2 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dorados de Sinaloa | 12 | 9 | 3 | 0 | 28:8 | 20 | 30 |
| 2 |
|
Atlante | 12 | 7 | 3 | 2 | 18:8 | 10 | 24 |
| 3 |
|
Atlético Morelia | 12 | 7 | 3 | 2 | 19:13 | 6 | 24 |
| 4 |
|
Cimarrones de Sonora | 12 | 6 | 2 | 4 | 17:13 | 4 | 20 |
| 5 |
|
Club Celaya | 12 | 6 | 2 | 4 | 13:9 | 4 | 20 |
| 6 |
|
Venados FC | 13 | 5 | 3 | 5 | 14:15 | -1 | 18 |
| 7 |
|
Pumas Tabasco | 12 | 4 | 5 | 3 | 12:12 | 0 | 17 |
| 8 |
|
TM Fútbol Club | 12 | 3 | 7 | 2 | 17:15 | 2 | 16 |
| 9 |
|
Leones Negros | 12 | 4 | 4 | 4 | 15:14 | 1 | 16 |
| 10 |
|
CF Monterrey II | 13 | 4 | 4 | 5 | 14:14 | 0 | 16 |
| 11 |
|
Tepatitlán | 12 | 3 | 4 | 5 | 13:16 | -3 | 13 |
| 12 |
|
Cancún FC | 12 | 3 | 3 | 6 | 9:12 | -3 | 12 |
| 13 |
|
Coyotes de Tlaxcala | 12 | 2 | 6 | 4 | 9:15 | -6 | 12 |
| 14 |
|
Correcaminos UAT | 12 | 3 | 3 | 6 | 13:22 | -9 | 12 |
| 15 |
|
Tapatío | 13 | 3 | 3 | 7 | 8:21 | -13 | 12 |
| 16 |
|
Mineros de Zacatecas | 12 | 3 | 1 | 8 | 16:23 | -7 | 10 |
| 17 |
|
Alebrijes de Oaxaca | 13 | 1 | 6 | 6 | 10:15 | -5 | 9 |
| Playoffs | |
| Playoffs |
