 |
 |
|
|
| 02/11/2021 | 23:00 | Coyotes de Tlaxcala | - | Cancún FC | 3:1 (0:0) | |
| 03/11/2021 | 01:05 | Club Celaya | - | Dorados de Sinaloa | 2:2 (1:0) | |
| 03:05 | Cimarrones de Sonora | - | Mineros de Zacatecas | 1:3 (0:0) | ||
| 23:00 | Alebrijes de Oaxaca | - | Correcaminos UAT | 2:1 (0:0) | ||
| 04/11/2021 | 01:05 | Venados FC | - | Leones Negros | 0:1 (0:1) | |
| 03:05 | TM Fútbol Club | - | Atlético Morelia | 1:1 (0:0) | ||
| 07/11/2021 | 16:00 | CF Monterrey II | - | Pumas Tabasco | 1:1 (1:1) | |
| 18:00 | Atlante | - | Tepatitlán | 1:0 (1:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dorados de Sinaloa | 14 | 10 | 4 | 0 | 33:10 | 23 | 34 |
| 2 |
|
Atlante | 14 | 8 | 4 | 2 | 19:8 | 11 | 28 |
| 3 |
|
Atlético Morelia | 14 | 7 | 4 | 3 | 20:15 | 5 | 25 |
| 4 |
|
Leones Negros | 14 | 6 | 4 | 4 | 17:14 | 3 | 22 |
| 5 |
|
Cimarrones de Sonora | 14 | 6 | 3 | 5 | 20:18 | 2 | 21 |
| 6 |
|
Club Celaya | 14 | 6 | 3 | 5 | 16:14 | 2 | 21 |
| 7 |
|
Pumas Tabasco | 14 | 5 | 6 | 3 | 14:13 | 1 | 21 |
| 8 |
|
TM Fútbol Club | 14 | 3 | 9 | 2 | 19:17 | 2 | 18 |
| 9 |
|
Venados FC | 15 | 5 | 3 | 7 | 14:19 | -5 | 18 |
| 10 |
|
CF Monterrey II | 14 | 4 | 5 | 5 | 15:15 | 0 | 17 |
| 11 |
|
Mineros de Zacatecas | 14 | 5 | 1 | 8 | 22:25 | -3 | 16 |
| 12 |
|
Coyotes de Tlaxcala | 14 | 3 | 6 | 5 | 12:17 | -5 | 15 |
| 13 |
|
Tepatitlán | 14 | 3 | 5 | 6 | 14:18 | -4 | 14 |
| 14 |
|
Alebrijes de Oaxaca | 15 | 2 | 7 | 6 | 12:16 | -4 | 13 |
| 15 |
|
Cancún FC | 14 | 3 | 4 | 7 | 12:17 | -5 | 13 |
| 16 |
|
Correcaminos UAT | 14 | 3 | 4 | 7 | 16:26 | -10 | 13 |
| 17 |
|
Tapatío | 14 | 3 | 4 | 7 | 10:23 | -13 | 13 |
| Playoffs | |
| Playoffs |
