 |
 |
|
|
| 21/09/2021 | 23:00 | CF Monterrey II | - | Mineros de Zacatecas | 0:1 (0:1) | |
| 22/09/2021 | 02:30 | Cancún FC | - | Leones Negros | 0:1 (0:1) | |
| 03:05 | Dorados de Sinaloa | - | Correcaminos UAT | 3:1 (1:0) | ||
| 23:00 | Coyotes de Tlaxcala | - | Tepatitlán | 0:0 (0:0) | ||
| 23/09/2021 | 01:05 | Pumas Tabasco | - | Venados FC | 1:1 (0:0) | |
| 03:05 | TM Fútbol Club | - | Cimarrones de Sonora | 1:2 (1:1) | ||
| 24/09/2021 | 01:00 | Atlético Morelia | - | Alebrijes de Oaxaca | 1:0 (1:0) | |
| 26/09/2021 | 23:00 | Tapatío | - | Atlante | 1:4 (0:3) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dorados de Sinaloa | 8 | 6 | 2 | 0 | 17:5 | 12 | 20 |
| 2 |
|
Atlante | 9 | 6 | 2 | 1 | 15:5 | 10 | 20 |
| 3 |
|
Atlético Morelia | 8 | 5 | 2 | 1 | 14:9 | 5 | 17 |
| 4 |
|
Pumas Tabasco | 8 | 4 | 2 | 2 | 9:8 | 1 | 14 |
| 5 |
|
TM Fútbol Club | 8 | 3 | 3 | 2 | 10:8 | 2 | 12 |
| 6 |
|
CF Monterrey II | 9 | 3 | 3 | 3 | 8:7 | 1 | 12 |
| 7 |
|
Club Celaya | 8 | 3 | 2 | 3 | 9:7 | 2 | 11 |
| 8 |
|
Coyotes de Tlaxcala | 9 | 2 | 5 | 2 | 7:7 | 0 | 11 |
| 9 |
|
Cimarrones de Sonora | 8 | 3 | 2 | 3 | 9:11 | -2 | 11 |
| 10 |
|
Venados FC | 9 | 3 | 2 | 4 | 7:10 | -3 | 11 |
| 11 |
|
Tepatitlán | 8 | 3 | 1 | 4 | 10:10 | 0 | 10 |
| 12 |
|
Mineros de Zacatecas | 9 | 3 | 1 | 5 | 14:15 | -1 | 10 |
| 13 |
|
Leones Negros | 8 | 2 | 3 | 3 | 10:10 | 0 | 9 |
| 14 |
|
Cancún FC | 8 | 3 | 0 | 5 | 7:9 | -2 | 9 |
| 15 |
|
Correcaminos UAT | 9 | 2 | 2 | 5 | 8:17 | -9 | 8 |
| 16 |
|
Alebrijes de Oaxaca | 9 | 1 | 4 | 4 | 7:10 | -3 | 7 |
| 17 |
|
Tapatío | 9 | 1 | 2 | 6 | 4:17 | -13 | 5 |
| Playoffs | |
| Playoffs |
