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| 21/09/2018 | 16:00 | Pumas UNAM II | - | Reboceros de La Piedad | 2:0 (2:0) | |
| 16:00 | CF América II | - | Yalmakan FC | 0:0 (0:0) | ||
| 22/09/2018 | 00:00 | Tecos Fútbol Club | - | Monarcas Morelia II | 0:0 (0:0) | |
| 02:30 | Dorados UACH | - | Atlético Reynosa | 0:0 (0:0) | ||
| 03:00 | Coras de Nayarit | - | Deportivo Guadalajara II | 1:0 (1:0) | ||
| 18:00 | Deportivo Toluca II | - | Pioneros de Cancún | 2:2 (2:2) | ||
| 22:00 | Albinegros Orizaba | - | Coyotes de Tlaxcala | 1:1 (1:1) | ||
| 22:00 | Tuzos de la UAZ | - | Real Zamora | 2:0 (2:0) | ||
| 22:00 | Tuxtla FC | - | Sporting Canamy | 5:0 (5:0) | ||
| 22:00 | Loros UCOL | - | Murciélagos FC | 1:2 (1:2) | ||
| 23:00 | Correcaminos UAT II | - | Tepatitlán | 2:0 (2:0) | ||
| 23:00 | Club Irapuato | - | Cocodrilos de Tabasco | 1:0 (1:0) | ||
| 23/09/2018 | 01:00 | Inter Playa | - | Cruz Azul Hidalgo | 2:1 (2:1) | |
| 16:00 | Gavilanes de Matamoros | - | Leones Negros II | 4:3 (4:3) | ||
| 24/10/2018 | 00:00 | Pacific F. C. | - | Club Necaxa II | 1:1 (1:1) | |
| 31/10/2018 | 02:00 | Alacranes de Durango | - | Cimarrones de Sonora II | 1:1 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 5 | 5 | 0 | 0 | 11:3 | 8 | 19 |
| 2 |
|
Tuxtla FC | 5 | 4 | 0 | 1 | 13:4 | 9 | 14 |
| 3 |
|
Deportivo Toluca II | 5 | 3 | 2 | 0 | 13:8 | 5 | 13 |
| 4 |
|
Murciélagos FC | 5 | 3 | 1 | 1 | 9:6 | 3 | 13 |
| 5 |
|
Pumas UNAM II | 5 | 3 | 0 | 2 | 10:5 | 5 | 12 |
| 6 |
|
Correcaminos UAT II | 5 | 2 | 3 | 0 | 8:3 | 5 | 12 |
| 7 |
|
Inter Playa | 5 | 3 | 1 | 1 | 9:6 | 3 | 12 |
| 8 |
|
Tepatitlán | 5 | 3 | 1 | 1 | 7:5 | 2 | 12 |
| 9 |
|
Deportivo Guadalajara II | 5 | 2 | 2 | 1 | 6:4 | 2 | 12 |
| 10 |
|
Dorados UACH | 5 | 2 | 2 | 1 | 7:7 | 0 | 12 |
| 11 |
|
Tuzos de la UAZ | 5 | 2 | 3 | 0 | 8:4 | 4 | 11 |
| 12 |
|
Loros UCOL | 5 | 1 | 2 | 2 | 8:7 | 1 | 11 |
| 13 |
|
Pacific F. C. | 5 | 2 | 2 | 1 | 9:6 | 3 | 10 |
| 14 |
|
Coras de Nayarit | 5 | 2 | 2 | 1 | 7:5 | 2 | 10 |
| 15 |
|
Cruz Azul Hidalgo | 5 | 2 | 0 | 3 | 8:8 | 0 | 10 |
| 16 |
|
Tecos Fútbol Club | 5 | 1 | 2 | 2 | 6:7 | -1 | 10 |
| 17 |
|
Gavilanes de Matamoros | 5 | 2 | 1 | 2 | 7:7 | 0 | 9 |
| 18 |
|
Club Necaxa II | 5 | 1 | 3 | 1 | 3:5 | -2 | 9 |
| 19 |
|
CF América II | 5 | 1 | 3 | 1 | 7:9 | -2 | 8 |
| 20 |
|
Real Zamora | 5 | 2 | 0 | 3 | 7:12 | -5 | 8 |
| 21 |
|
Monarcas Morelia II | 5 | 1 | 3 | 1 | 9:4 | 5 | 7 |
| 22 |
|
Pioneros de Cancún | 5 | 1 | 2 | 2 | 8:10 | -2 | 7 |
| 23 |
|
Atlético Reynosa | 5 | 0 | 3 | 2 | 2:4 | -2 | 7 |
| 24 |
|
Coyotes de Tlaxcala | 5 | 1 | 2 | 2 | 3:6 | -3 | 7 |
| 25 |
|
Albinegros Orizaba | 5 | 1 | 2 | 2 | 3:5 | -2 | 6 |
| 26 |
|
Alacranes de Durango | 5 | 1 | 2 | 2 | 4:7 | -3 | 6 |
| 27 |
|
Reboceros de La Piedad | 5 | 0 | 2 | 3 | 6:11 | -5 | 6 |
| 28 |
|
Leones Negros II | 5 | 1 | 1 | 3 | 7:10 | -3 | 5 |
| 29 |
|
Cocodrilos de Tabasco | 5 | 0 | 2 | 3 | 6:9 | -3 | 5 |
| 30 |
|
Sporting Canamy | 5 | 1 | 1 | 3 | 4:11 | -7 | 5 |
| 31 |
|
Yalmakan FC | 5 | 0 | 2 | 3 | 1:6 | -5 | 4 |
| 32 |
|
Cimarrones de Sonora II | 5 | 0 | 2 | 3 | 3:15 | -12 | 2 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Relegation |
