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| 1st(1st leg) | Monarcas Morelia | - | Club León | 3:3 (2:2) | ||
| 2nd (2nd leg) | Club León | - | Monarcas Morelia | 1:2 (0:0) | ||
| 1st(1st leg): 28/11/2019 01:00 | 2nd (2nd leg): 01/12/2019 01:00 | Winner: Monarcas Morelia | ||||
| 1st(1st leg) | Club Necaxa | - | Gallos Blancos | 3:0 (0:0) | ||
| 2nd (2nd leg) | Gallos Blancos | - | Club Necaxa | 2:3 (2:0) | ||
| 1st(1st leg): 28/11/2019 03:00 | 2nd (2nd leg): 01/12/2019 03:05 | Winner: Club Necaxa | ||||
| 1st(1st leg) | CF Monterrey | - | Santos Laguna | 5:2 (2:2) | ||
| 2nd (2nd leg) | Santos Laguna | - | CF Monterrey | 1:1 (1:0) | ||
| 1st(1st leg): 29/11/2019 01:06 | 2nd (2nd leg): 02/12/2019 01:00 | Winner: CF Monterrey | ||||
| 1st(1st leg) | CF América | - | UANL Tigres | 1:2 (1:0) | ||
| 2nd (2nd leg) | UANL Tigres | - | CF América | 2:4 (0:3) | ||
| 1st(1st leg): 29/11/2019 03:00 | 2nd (2nd leg): 02/12/2019 03:00 | Winner: CF América | ||||
