 |
 |
|
|
| 19/02/2021 | 03:00 | Atlético San Luis | - | Santos Laguna | 1:0 (1:0) | |
| 20/02/2021 | 01:30 | Club Necaxa | - | CF Monterrey | 1:1 (0:1) | |
| 03:30 | FC Juárez | - | Mazatlán FC | 1:0 (0:0) | ||
| 21/02/2021 | 01:00 | Cruz Azul | - | Deportivo Toluca | 3:2 (2:2) | |
| 03:00 | Atlas Guadalajara | - | CF América | 3:0 dec. | ||
| 18:00 | Pumas UNAM | - | Club León | 0:1 (0:0) | ||
| 23:00 | Gallos Blancos | - | Puebla FC | 1:1 (0:0) | ||
| 22/02/2021 | 01:00 | UANL Tigres | - | Club Tijuana | 3:2 (2:0) | |
| 23/02/2021 | 03:00 | CF Pachuca | - | Deportivo Guadalajara | 1:1 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cruz Azul | 7 | 5 | 0 | 2 | 12:5 | 7 | 15 |
| 2 |
|
Deportivo Toluca | 7 | 4 | 1 | 2 | 15:9 | 6 | 13 |
| 3 |
|
UANL Tigres | 7 | 4 | 1 | 2 | 11:9 | 2 | 13 |
| 4 |
|
CF América | 7 | 4 | 1 | 2 | 8:7 | 1 | 13 |
| 5 |
|
Club Tijuana | 7 | 3 | 3 | 1 | 10:7 | 3 | 12 |
| 6 |
|
CF Monterrey | 7 | 3 | 3 | 1 | 6:3 | 3 | 12 |
|
Santos Laguna | 7 | 3 | 3 | 1 | 6:3 | 3 | 12 | |
| 8 |
|
Atlético San Luis | 7 | 3 | 1 | 3 | 11:9 | 2 | 10 |
| 9 |
|
Gallos Blancos | 7 | 3 | 1 | 3 | 10:11 | -1 | 10 |
| 10 |
|
Puebla FC | 7 | 2 | 3 | 2 | 7:4 | 3 | 9 |
| 11 |
|
Atlas Guadalajara | 7 | 2 | 2 | 3 | 5:6 | -1 | 8 |
| 12 |
|
Club León | 7 | 2 | 2 | 3 | 6:9 | -3 | 8 |
| 13 |
|
FC Juárez | 7 | 2 | 2 | 3 | 6:11 | -5 | 8 |
| 14 |
|
Deportivo Guadalajara | 7 | 1 | 4 | 2 | 10:11 | -1 | 7 |
| 15 |
|
Mazatlán FC | 7 | 2 | 1 | 4 | 5:13 | -8 | 7 |
| 16 |
|
Club Necaxa | 7 | 1 | 3 | 3 | 7:11 | -4 | 6 |
| 17 |
|
Pumas UNAM | 7 | 1 | 2 | 4 | 3:5 | -2 | 5 |
| 18 |
|
CF Pachuca | 7 | 0 | 3 | 4 | 3:8 | -5 | 3 |
| Playoffs | |
| Playoffs |
