 |
 |
|
| 01/10/2022 | 01:00 | Puebla FC | - | CF América | 1:2 (0:1) | |
| 03:00 | FC Juárez | - | Pumas UNAM | 3:1 (2:1) | ||
| 23:00 | Atlético San Luis | - | UANL Tigres | 0:3 (0:0) | ||
| 23:05 | CF Monterrey | - | CF Pachuca | 0:0 (0:0) | ||
| 02/10/2022 | 01:05 | Atlas Guadalajara | - | Club Necaxa | 1:0 (0:0) | |
| 03:05 | Cruz Azul | - | Deportivo Guadalajara | 2:1 (1:0) | ||
| 18:00 | Deportivo Toluca | - | Gallos Blancos | 4:1 (2:0) | ||
| 03/10/2022 | 00:05 | Santos Laguna | - | Mazatlán FC | 3:0 (0:0) | |
| 02:00 | Club León | - | Club Tijuana | 2:2 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF América | 17 | 12 | 2 | 3 | 38:17 | 21 | 38 |
| 2 |
|
CF Monterrey | 17 | 10 | 5 | 2 | 29:13 | 16 | 35 |
| 3 |
|
Santos Laguna | 17 | 10 | 3 | 4 | 38:21 | 17 | 33 |
| 4 |
|
CF Pachuca | 17 | 9 | 5 | 3 | 28:15 | 13 | 32 |
| 5 |
|
UANL Tigres | 17 | 9 | 3 | 5 | 24:14 | 10 | 30 |
| 6 |
|
Deportivo Toluca | 17 | 7 | 6 | 4 | 27:23 | 4 | 27 |
| 7 |
|
Cruz Azul | 17 | 7 | 3 | 7 | 26:34 | -8 | 24 |
| 8 |
|
Puebla FC | 17 | 4 | 10 | 3 | 25:23 | 2 | 22 |
| 9 |
|
Deportivo Guadalajara | 17 | 5 | 7 | 5 | 19:17 | 2 | 22 |
| 10 |
|
Club León | 17 | 6 | 4 | 7 | 25:29 | -4 | 22 |
| 11 |
|
FC Juárez | 17 | 4 | 7 | 6 | 17:18 | -1 | 19 |
| 12 |
|
Club Necaxa | 17 | 5 | 4 | 8 | 19:26 | -7 | 19 |
| 13 |
|
Atlético San Luis | 17 | 4 | 6 | 7 | 15:23 | -8 | 18 |
| 14 |
|
Mazatlán FC | 17 | 3 | 8 | 6 | 17:24 | -7 | 17 |
| 15 |
|
Club Tijuana | 17 | 4 | 5 | 8 | 18:30 | -12 | 17 |
| 16 |
|
Pumas UNAM | 17 | 2 | 8 | 7 | 21:31 | -10 | 14 |
| 17 |
|
Atlas Guadalajara | 17 | 3 | 4 | 10 | 16:27 | -11 | 13 |
| 18 |
|
Gallos Blancos | 17 | 1 | 6 | 10 | 18:35 | -17 | 9 |
| Playoffs | |
| Playoffs |
