 |
 |
|
|
| 1st(1st leg) | Deportivo Toluca | - | CF Pachuca | 0:2 (0:1) | ||
| 2nd (2nd leg) | CF Pachuca | - | Deportivo Toluca | 0:2 (0:0) | ||
| 1st(1st leg): 12/05/2021 15:00 | 2nd (2nd leg): 15/05/2021 16:00 | |||||
| 1st(1st leg) | Atlas Guadalajara | - | CF Monterrey | 1:2 (1:0) | ||
| 2nd (2nd leg) | CF Monterrey | - | Atlas Guadalajara | 1:0 (0:0) | ||
| 1st(1st leg): 13/05/2021 15:00 | 2nd (2nd leg): 16/05/2021 15:00 | Winner: CF Monterrey | ||||
