 |
 |
|
|
| 01/03/2022 | 15:00 | Deportivo Toluca | - | Club Tijuana | 3:1 (1:1) | |
| 15:00 | Puebla FC | - | FC Juárez | 2:2 (0:0) | ||
| 15:00 | Club León | - | CF Monterrey | 1:2 (1:0) | ||
| 15:00 | CF América | - | Gallos Blancos | 2:0 (0:0) | ||
| 16:00 | Mazatlán FC | - | Club Necaxa | 1:3 (0:1) | ||
| 02/03/2022 | 15:00 | UANL Tigres | - | Cruz Azul | 1:1 (1:0) | |
| 15:00 | Atlas Guadalajara | - | CF Pachuca | 0:3 (0:0) | ||
| 15:00 | Atlético San Luis | - | Deportivo Guadalajara | 2:3 (2:2) | ||
| 17:00 | Santos Laguna | - | Pumas UNAM | 2:1 (2:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 8 | 6 | 0 | 2 | 18:11 | 7 | 18 |
| 2 |
|
UANL Tigres | 8 | 5 | 2 | 1 | 18:8 | 10 | 17 |
| 3 |
|
Atlético San Luis | 8 | 5 | 1 | 2 | 21:10 | 11 | 16 |
| 4 |
|
Club León | 8 | 5 | 1 | 2 | 17:10 | 7 | 16 |
| 5 |
|
Club Tijuana | 8 | 5 | 1 | 2 | 12:8 | 4 | 16 |
| 6 |
|
Deportivo Guadalajara | 8 | 5 | 1 | 2 | 10:8 | 2 | 16 |
| 7 |
|
Deportivo Toluca | 8 | 4 | 2 | 2 | 14:10 | 4 | 14 |
| 8 |
|
CF América | 8 | 4 | 1 | 3 | 13:7 | 6 | 13 |
| 9 |
|
Pumas UNAM | 8 | 3 | 3 | 2 | 8:7 | 1 | 12 |
| 10 |
|
Club Necaxa | 8 | 3 | 1 | 4 | 12:12 | 0 | 10 |
| 11 |
|
Santos Laguna | 8 | 3 | 1 | 4 | 9:14 | -5 | 10 |
| 12 |
|
CF Monterrey | 8 | 2 | 3 | 3 | 7:13 | -6 | 9 |
| 13 |
|
Cruz Azul | 8 | 1 | 4 | 3 | 7:9 | -2 | 7 |
| 14 |
|
Mazatlán FC | 8 | 2 | 1 | 5 | 8:13 | -5 | 7 |
| 15 |
|
Puebla FC | 8 | 2 | 1 | 5 | 10:17 | -7 | 7 |
| 16 |
|
Atlas Guadalajara | 8 | 1 | 2 | 5 | 6:14 | -8 | 5 |
| 17 |
|
FC Juárez | 8 | 1 | 2 | 5 | 8:20 | -12 | 5 |
| 18 |
|
Gallos Blancos | 8 | 0 | 3 | 5 | 1:8 | -7 | 3 |
| Playoffs |
