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| 23/10/2021 | 11:30 | FC Groningen | - | NEC Nijmegen | 3:1 | |
| 13:45 | NAC Breda | - | Amsterdamsche FC | 1:1 | ||
| 14:00 | ADO Den Haag | - | Vitesse | 3:0 | ||
| 14:00 | Twente/Heracles | - | FC Volendam | 8:1 |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Groningen | 7 | 5 | 2 | 0 | 15:4 | 11 | 17 |
| 2 |
|
NAC Breda | 7 | 5 | 2 | 0 | 17:8 | 9 | 17 |
| 3 |
|
Twente/Heracles | 7 | 4 | 0 | 3 | 24:12 | 12 | 12 |
| 4 |
|
Amsterdamsche FC | 7 | 3 | 2 | 2 | 16:19 | -3 | 11 |
| 5 |
|
ADO Den Haag | 7 | 2 | 2 | 3 | 10:9 | 1 | 8 |
| 6 |
|
NEC Nijmegen | 7 | 2 | 1 | 4 | 17:21 | -4 | 7 |
| 7 |
|
Vitesse | 7 | 2 | 0 | 5 | 11:17 | -6 | 6 |
| 8 |
|
FC Volendam | 7 | 0 | 1 | 6 | 6:26 | -20 | 1 |
| Promotion | |
| Relegation |
