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| 08/10/2021 | 18:00 | FSV 08 Bietigheim-Bissingen | - | FC Nöttingen | 2:1 (0:1) | |
| 09/10/2021 | 13:00 | 1. CfR Pforzheim | - | SGV Freiberg | 0:4 (0:2) | |
| 13:00 | Göppinger SV | - | FV Lörrach-Brombach | 2:1 (0:1) | ||
| 13:00 | Neckarsulmer Sport-Union | - | SSV Reutlingen | 2:2 (0:1) | ||
| 13:00 | TSV Ilshofen | - | Stuttgarter Kickers | 0:3 (0:1) | ||
| 13:30 | Freiburger FC | - | FC-Astoria Walldorf II | 0:1 (0:0) | ||
| 14:30 | 1. FC Bruchsal | - | SV Oberachern | 0:2 (0:0) | ||
| 14:30 | FC 08 Villingen | - | Sportfreunde Dorfmerkingen | 1:3 (0:1) | ||
| 14:30 | SV Linx | - | FV Ravensburg | 1:1 (1:0) | ||
| 10/10/2021 | 14:00 | 1. FC Rielasingen-Arlen | - | TSG Backnang | 2:1 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Stuttgarter Kickers | 12 | 8 | 2 | 2 | 22:6 | 16 | 26 |
| 2 |
|
SGV Freiberg | 12 | 7 | 4 | 1 | 36:10 | 26 | 25 |
| 3 |
|
FSV 08 Bietigheim-Bissingen | 12 | 7 | 3 | 2 | 31:11 | 20 | 24 |
| 4 |
|
TSG Backnang | 12 | 7 | 1 | 4 | 25:17 | 8 | 22 |
| 5 |
|
Göppinger SV | 12 | 6 | 4 | 2 | 19:13 | 6 | 22 |
| 6 |
|
FC 08 Villingen | 12 | 6 | 2 | 4 | 20:16 | 4 | 20 |
| 7 |
|
1. FC Rielasingen-Arlen | 12 | 6 | 2 | 4 | 14:13 | 1 | 20 |
| 8 |
|
FC-Astoria Walldorf II | 12 | 6 | 2 | 4 | 19:19 | 0 | 20 |
| 9 |
|
1. CfR Pforzheim | 12 | 6 | 1 | 5 | 18:17 | 1 | 19 |
| 10 |
|
FV Ravensburg | 12 | 5 | 3 | 4 | 28:20 | 8 | 18 |
| 11 |
|
Neckarsulmer Sport-Union | 12 | 5 | 3 | 4 | 20:18 | 2 | 18 |
| 12 |
|
SV Linx | 12 | 4 | 3 | 5 | 12:28 | -16 | 15 |
| 13 |
|
FC Nöttingen | 12 | 4 | 2 | 6 | 23:21 | 2 | 14 |
| 14 |
|
SSV Reutlingen | 12 | 3 | 4 | 5 | 16:19 | -3 | 13 |
| 15 |
|
Freiburger FC | 12 | 3 | 4 | 5 | 14:18 | -4 | 13 |
| 16 |
|
SV Oberachern | 12 | 4 | 1 | 7 | 18:25 | -7 | 13 |
| 17 |
|
Sportfreunde Dorfmerkingen | 12 | 3 | 3 | 6 | 13:27 | -14 | 12 |
| 18 |
|
TSV Ilshofen | 12 | 2 | 2 | 8 | 13:27 | -14 | 8 |
| 19 |
|
1. FC Bruchsal | 12 | 2 | 2 | 8 | 12:28 | -16 | 8 |
| 20 |
|
FV Lörrach-Brombach | 12 | 1 | 2 | 9 | 7:27 | -20 | 5 |
| Promotion | |
| Playoffs | |
| Relegation |
