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| 09/10/2020 | 13:00 | Bor. Mönchengladbach II | - | 1. FC Köln II | 1:2 (0:1) | |
| 10/10/2020 | 13:00 | Alemannia Aachen | - | Rot-Weiß Oberhausen | 2:1 (1:0) | |
| 13:00 | Borussia Dortmund II | - | FC Wegberg-Beeck | 3:2 (1:1) | ||
| 13:00 | Fortuna Düsseldorf II | - | SC Wiedenbrück | 1:1 (0:0) | ||
| 13:00 | Fortuna Köln | - | Rot-Weiss Essen | 1:1 (0:1) | ||
| 13:00 | Preußen Münster | - | Sportfreunde Lotte | 4:1 (2:1) | ||
| 13:00 | SV Bergisch Gladbach 09 | - | SV 19 Straelen | 0:1 (0:0) | ||
| 13:00 | SV Lippstadt 08 | - | Bonner SC | 0:1 (0:1) | ||
| 14:30 | FC Schalke 04 II | - | Wuppertaler SV | 1:2 (0:1) | ||
| 28/10/2020 | 18:30 | SV Rödinghausen | - | VfB Homberg | 4:0 (3:0) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 8 | 5 | 2 | 1 | 15:6 | 9 | 17 |
| 2 |
|
Borussia Dortmund II | 7 | 5 | 2 | 0 | 14:6 | 8 | 17 |
|
Fortuna Köln | 8 | 5 | 2 | 1 | 14:6 | 8 | 17 | |
| 4 |
|
Fortuna Düsseldorf II | 8 | 4 | 3 | 1 | 17:4 | 13 | 15 |
| 5 |
|
Rot-Weiss Essen | 7 | 4 | 3 | 0 | 12:5 | 7 | 15 |
| 6 |
|
Bor. Mönchengladbach II | 8 | 4 | 2 | 2 | 15:9 | 6 | 14 |
| 7 |
|
SV Rödinghausen | 8 | 3 | 3 | 2 | 10:7 | 3 | 12 |
| 8 |
|
FC Schalke 04 II | 8 | 3 | 2 | 3 | 8:7 | 1 | 11 |
| 9 |
|
Wuppertaler SV | 8 | 3 | 2 | 3 | 12:15 | -3 | 11 |
| 10 |
|
1. FC Köln II | 7 | 2 | 4 | 1 | 7:6 | 1 | 10 |
| 11 |
|
SC Wiedenbrück | 7 | 2 | 4 | 1 | 9:9 | 0 | 10 |
| 12 |
|
Alemannia Aachen | 8 | 3 | 1 | 4 | 5:7 | -2 | 10 |
| 13 |
|
SV 19 Straelen | 8 | 2 | 3 | 3 | 9:12 | -3 | 9 |
| 14 |
|
Bonner SC | 7 | 2 | 2 | 3 | 8:10 | -2 | 8 |
| 15 |
|
SV Lippstadt 08 | 8 | 1 | 5 | 2 | 7:9 | -2 | 8 |
| 16 |
|
Rot-Weiß Oberhausen | 8 | 1 | 4 | 3 | 6:10 | -4 | 7 |
| 17 |
|
SV Bergisch Gladbach 09 | 8 | 1 | 3 | 4 | 5:11 | -6 | 6 |
| 18 |
|
Sportfreunde Lotte | 7 | 1 | 2 | 4 | 7:18 | -11 | 5 |
| 19 |
|
Rot Weiss Ahlen | 7 | 1 | 1 | 5 | 9:14 | -5 | 4 |
| 20 |
|
FC Wegberg-Beeck | 7 | 1 | 1 | 5 | 6:11 | -5 | 4 |
| 21 |
|
VfB Homberg | 8 | 1 | 1 | 6 | 6:19 | -13 | 4 |
| Promotion | |
| Relegation |
