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| 16/09/2022 | 18:00 | SG Wattenscheid 09 | - | SV 19 Straelen | 0:4 (0:2) | |
| 17/09/2022 | 13:00 | Preußen Münster | - | SV Rödinghausen | 1:0 (0:0) | |
| 13:00 | Fortuna Düsseldorf II | - | FC Schalke 04 II | 2:4 (1:2) | ||
| 13:00 | 1. FC Düren | - | 1. FC Kaan-Marienborn | 3:0 (3:0) | ||
| 13:00 | 1. FC Bocholt | - | Alemannia Aachen | 2:0 (0:0) | ||
| 13:00 | SC Wiedenbrück | - | Bor. Mönchengladbach II | 1:2 (0:0) | ||
| 13:00 | Wuppertaler SV | - | SV Lippstadt 08 | 5:1 (2:1) | ||
| 18/09/2022 | 13:00 | Fortuna Köln | - | Rot-Weiß Oberhausen | 1:1 (1:1) | |
| 13:00 | Rot Weiss Ahlen | - | 1. FC Köln II | 1:3 (0:2) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 9 | 7 | 1 | 1 | 23:8 | 15 | 22 |
| 2 |
|
SV Rödinghausen | 9 | 6 | 0 | 3 | 21:7 | 14 | 18 |
| 3 |
|
1. FC Kaan-Marienborn | 9 | 5 | 2 | 2 | 14:13 | 1 | 17 |
| 4 |
|
FC Schalke 04 II | 9 | 5 | 1 | 3 | 17:12 | 5 | 16 |
| 5 |
|
1. FC Düren | 9 | 5 | 1 | 3 | 14:14 | 0 | 16 |
| 6 |
|
Alemannia Aachen | 9 | 4 | 3 | 2 | 14:12 | 2 | 15 |
| 7 |
|
Wuppertaler SV | 9 | 3 | 4 | 2 | 17:11 | 6 | 13 |
| 8 |
|
Bor. Mönchengladbach II | 9 | 3 | 4 | 2 | 14:11 | 3 | 13 |
| 9 |
|
1. FC Köln II | 9 | 4 | 1 | 4 | 18:20 | -2 | 13 |
| 10 |
|
Fortuna Köln | 9 | 3 | 3 | 3 | 7:8 | -1 | 12 |
| 11 |
|
Rot-Weiß Oberhausen | 9 | 3 | 3 | 3 | 16:21 | -5 | 12 |
| 12 |
|
SV Lippstadt 08 | 9 | 4 | 0 | 5 | 13:19 | -6 | 12 |
| 13 |
|
SC Wiedenbrück | 9 | 3 | 2 | 4 | 14:11 | 3 | 11 |
| 14 |
|
Rot Weiss Ahlen | 9 | 3 | 2 | 4 | 17:15 | 2 | 11 |
| 15 |
|
Fortuna Düsseldorf II | 9 | 3 | 1 | 5 | 13:19 | -6 | 10 |
| 16 |
|
1. FC Bocholt | 9 | 2 | 2 | 5 | 12:19 | -7 | 8 |
| 17 |
|
SG Wattenscheid 09 | 9 | 1 | 2 | 6 | 10:27 | -17 | 5 |
| 18 |
|
SV 19 Straelen | 9 | 1 | 0 | 8 | 6:13 | -7 | 3 |
| Promotion | |
| Relegation | |
| Relegation |
