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| 14/04/2021 | 10:00 | CSKA Moskva | - | Akhmat Grozny | 8:1 (3:1) | |
| 10:00 | Rubin Kazan | - | FK Krasnodar | 0:3 (0:1) | ||
| 10:00 | Zenit St. Petersburg | - | PFC Sochi | 3:1 (1:0) | ||
| 11:00 | Lokomotiv Moskva | - | FK Rostov | 2:0 (1:0) | ||
| 15:30 | FK Strogino Moskva | - | Spartak Moskva | 0:4 (0:2) |
| » Tables | Home | Away | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 21 | 18 | 1 | 2 | 66:19 | 47 | 55 |
| 2 |
|
FK Krasnodar | 21 | 17 | 2 | 2 | 47:15 | 32 | 53 |
| 3 |
|
Zenit St. Petersburg | 21 | 17 | 2 | 2 | 59:17 | 42 | 53 |
| 4 |
|
Spartak Moskva | 21 | 14 | 4 | 3 | 43:18 | 25 | 46 |
| 5 |
|
Lokomotiv Moskva | 21 | 12 | 3 | 6 | 41:17 | 24 | 39 |
| 6 |
|
Akhmat Grozny | 21 | 11 | 6 | 4 | 38:28 | 10 | 39 |
| 7 |
|
Rubin Kazan | 21 | 9 | 5 | 7 | 26:22 | 4 | 32 |
| 8 |
|
PFC Sochi | 21 | 7 | 7 | 7 | 27:26 | 1 | 28 |
| 9 |
|
FK Rostov | 21 | 6 | 6 | 9 | 32:34 | -2 | 24 |
| 10 |
|
FK Strogino Moskva | 21 | 7 | 3 | 11 | 32:42 | -10 | 24 |
