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| 15/10/2010 | 17:00 | Partizan | - | FK Smederevo | 5:3 (2:1) | |
| 16/10/2010 | 13:30 | FK Inđija | - | FK Javor | 1:1 (1:0) | |
| 13:30 | FK Čukarički | - | BSK Borča | 0:0 (0:0) | ||
| 13:30 | FK Metalac | - | FK Jagodina | 1:2 (1:1) | ||
| 13:30 | OFK Beograd | - | Spartak Zlatibor Voda | 2:0 (0:0) | ||
| 17/10/2010 | 13:30 | Hajduk Rodić | - | Vojvodina | 0:1 (0:0) | |
| 13:30 | FK Rad Beograd | - | Borac Čačak | 3:1 (0:1) | ||
| 14:00 | FK Sloboda Point Sevojno | - | Crvena Zvezda | 0:3 (0:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Crvena Zvezda | 8 | 7 | 1 | 0 | 13:2 | 11 | 22 |
| 2 |
|
Partizan | 8 | 6 | 1 | 1 | 16:6 | 10 | 19 |
| 3 |
|
Vojvodina | 8 | 5 | 3 | 0 | 10:1 | 9 | 18 |
| 4 |
|
FK Rad Beograd | 8 | 5 | 2 | 1 | 11:4 | 7 | 17 |
| 5 |
|
Spartak Zlatibor Voda | 8 | 3 | 4 | 1 | 7:5 | 2 | 13 |
| 6 |
|
OFK Beograd | 8 | 4 | 1 | 3 | 8:7 | 1 | 13 |
| 7 |
|
FK Jagodina | 8 | 3 | 3 | 2 | 7:6 | 1 | 12 |
| 8 |
|
FK Sloboda Point Sevojno | 8 | 2 | 5 | 1 | 5:6 | -1 | 11 |
| 9 |
|
FK Smederevo | 8 | 2 | 4 | 2 | 9:7 | 2 | 10 |
| 10 |
|
Borac Čačak | 8 | 2 | 4 | 2 | 6:8 | -2 | 10 |
| 11 |
|
FK Inđija | 8 | 2 | 2 | 4 | 8:9 | -1 | 8 |
| 12 |
|
BSK Borča | 8 | 1 | 4 | 3 | 4:9 | -5 | 7 |
| 13 |
|
FK Javor | 8 | 0 | 5 | 3 | 2:6 | -4 | 5 |
| 14 |
|
FK Metalac | 8 | 0 | 2 | 6 | 2:11 | -9 | 2 |
| 15 |
|
FK Čukarički | 8 | 0 | 2 | 6 | 1:13 | -12 | 2 |
| 16 |
|
Hajduk Rodić | 8 | 0 | 1 | 7 | 4:13 | -9 | 1 |
| Champions League Quali. | |
| Europa League | |
| Relegation |
