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| 30/04/2022 | 15:00 | FK Novi Pazar | - | FK Radnički 1923 | 2:1 (0:1) | |
| 17:30 | FK Kolubara | - | Mladost Lučani | 3:0 (2:0) | ||
| 02/05/2022 | 14:00 | Radnik Surdulica | - | Spartak Subotica | 2:0 (1:0) | |
| 16:05 | Proleter Novi Sad | - | FK Metalac | 0:0 (0:0) |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Kolubara | 34 | 13 | 4 | 17 | 40:60 | -20 | 43 |
| 2 |
|
Radnik Surdulica | 34 | 9 | 15 | 10 | 30:35 | -5 | 42 |
| 3 |
|
Mladost Lučani | 34 | 10 | 9 | 15 | 39:48 | -9 | 39 |
| 4 |
|
Spartak Subotica | 34 | 10 | 8 | 16 | 40:56 | -16 | 38 |
| 5 |
|
FK Novi Pazar | 34 | 8 | 11 | 15 | 34:53 | -19 | 35 |
| 6 |
|
FK Radnički 1923 | 34 | 8 | 8 | 18 | 30:55 | -25 | 32 |
| 7 |
|
Proleter Novi Sad | 34 | 8 | 8 | 18 | 24:52 | -28 | 32 |
| 8 |
|
FK Metalac | 34 | 7 | 9 | 18 | 40:58 | -18 | 30 |
| Playoffs | |
| Relegation |
