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| 20/11/2010 | 14:00 | FC Tuggen | - | FC Zürich | 0:4 (0:3) | |
| 18:00 | Servette FC | - | FC Basel | 3:4 (0:1, 1:1, 1:1) pso | ||
| 18:00 | FC St. Gallen | - | FC Thun | 0:1 (0:0) | ||
| 21/11/2010 | 13:30 | FC Lugano | - | FC Sion | 2:3 (0:1, 1:1) aet | |
| 14:00 | FC Wohlen | - | Grasshopper Club Zürich | 1:2 (0:2) | ||
| 14:00 | Neuchâtel Xamax FC | - | AC Bellinzona | 1:0 (1:0) | ||
| 14:00 | SC Kriens | - | BSC Young Boys | 1:2 (1:1) | ||
| 14:00 | FC Biel/Bienne | - | FC Luzern | 5:3 (2:0, 2:2, 2:2) pso |
