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| 05/12/2021 | Kastamonuspor | - | 24 Erzincanspor | dnp | ||
| 10:00 | Amed SK | - | Tarsus Idman Yurdu | 1:0 (1:0) | ||
| 10:00 | Ankara Demirspor | - | Nazilli Belediyespor | 0:0 (0:0) | ||
| 10:00 | Eskişehirspor | - | Kırşehir Belediyespor | 1:1 (1:0) | ||
| 10:00 | Karacabey Belediyespor | - | Uşakspor | 1:0 (0:0) | ||
| 10:00 | Pazarspor | - | Isparta 32 SK | 2:0 (1:0) | ||
| 10:00 | Zonguldak Kömürspor | - | 1922 Konyaspor | 2:1 (1:0) | ||
| 06/12/2021 | 10:00 | Kırklarelispor | - | Akhisar Belediyespor | 5:1 (2:1) | |
| 10:00 | Şanlıurfaspor | - | Pendikspor | 0:0 (0:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pendikspor | 14 | 10 | 3 | 1 | 22:9 | 13 | 33 |
| 2 |
|
Amed SK | 14 | 7 | 3 | 4 | 20:18 | 2 | 24 |
| 3 |
|
Kırklarelispor | 14 | 5 | 7 | 2 | 24:15 | 9 | 22 |
| 4 |
|
Bucaspor 1928 | 14 | 7 | 1 | 6 | 21:18 | 3 | 22 |
| 5 |
|
Isparta 32 SK | 15 | 6 | 4 | 5 | 14:11 | 3 | 22 |
| 6 |
|
Pazarspor | 14 | 7 | 1 | 6 | 22:20 | 2 | 22 |
| 7 |
|
Şanlıurfaspor | 14 | 5 | 6 | 3 | 18:16 | 2 | 21 |
| 8 |
|
Ankara Demirspor | 15 | 5 | 5 | 5 | 13:13 | 0 | 20 |
|
Nazilli Belediyespor | 14 | 5 | 5 | 4 | 13:13 | 0 | 20 | |
| 10 |
|
Uşakspor | 14 | 5 | 4 | 5 | 13:17 | -4 | 19 |
| 11 |
|
Tarsus Idman Yurdu | 15 | 5 | 3 | 7 | 13:15 | -2 | 18 |
| 12 |
|
1922 Konyaspor | 15 | 4 | 5 | 6 | 22:20 | 2 | 17 |
| 13 |
|
24 Erzincanspor | 14 | 4 | 5 | 5 | 18:16 | 2 | 17 |
| 14 |
|
Kırşehir Belediyespor | 14 | 4 | 5 | 5 | 14:14 | 0 | 17 |
| 15 |
|
Zonguldak Kömürspor | 14 | 5 | 2 | 7 | 17:21 | -4 | 17 |
| 16 |
|
Akhisar Belediyespor | 15 | 5 | 2 | 8 | 17:23 | -6 | 17 |
| 17 |
|
Karacabey Belediyespor | 14 | 5 | 1 | 8 | 21:24 | -3 | 16 |
| 18 |
|
Eskişehirspor | 15 | 3 | 2 | 10 | 14:33 | -19 | 8 |
| 19 |
|
Kastamonuspor | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotion | |
| Playoffs | |
| Relegation |
