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| 31/10/2021 | 10:00 | Serik Belediyespor | - | Hekimoğlu Trabzon | 0:2 (0:0) | |
| 11:00 | Bayburt İl Özel İdare | - | Vanspor FK | 5:0 (1:0) | ||
| 11:00 | Ergene Velimeşe | - | Adıyamanspor | 2:1 (1:0) | ||
| 11:00 | Etimesgut Belediyespor | - | Çorum FK | 0:2 (0:0) | ||
| 11:00 | Kahramanmaraşspor | - | Ankaraspor | 0:1 (0:1) | ||
| 11:00 | Sarıyer SK | - | Bodrumspor | 1:2 (0:1) | ||
| 11:00 | Sivas Belediyespor | - | Somaspor | 2:3 (1:0) | ||
| 11:00 | Turgutluspor | - | Inegölspor | 1:0 (0:0) | ||
| 15:00 | Diyarbekirspor | - | Afjet Afyonspor | 1:1 (1:1) | ||
| 01/11/2021 | 16:00 | Sakaryaspor | - | Niğde Anadolu FK | 4:0 (3:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hekimoğlu Trabzon | 10 | 6 | 4 | 0 | 19:6 | 13 | 22 |
| 2 |
|
Sivas Belediyespor | 10 | 6 | 3 | 1 | 19:4 | 15 | 21 |
| 3 |
|
Çorum FK | 10 | 6 | 3 | 1 | 17:4 | 13 | 21 |
| 4 |
|
Sakaryaspor | 10 | 5 | 5 | 0 | 17:2 | 15 | 20 |
| 5 |
|
Ankaraspor | 10 | 6 | 2 | 2 | 23:11 | 12 | 20 |
| 6 |
|
Bayburt İl Özel İdare | 10 | 6 | 2 | 2 | 16:8 | 8 | 20 |
| 7 |
|
Vanspor FK | 10 | 6 | 2 | 2 | 17:14 | 3 | 20 |
| 8 |
|
Bodrumspor | 10 | 6 | 1 | 3 | 18:7 | 11 | 19 |
| 9 |
|
Somaspor | 10 | 5 | 2 | 3 | 16:13 | 3 | 17 |
| 10 |
|
Afjet Afyonspor | 10 | 3 | 6 | 1 | 16:13 | 3 | 15 |
| 11 |
|
Etimesgut Belediyespor | 10 | 4 | 2 | 4 | 12:14 | -2 | 14 |
| 12 |
|
Serik Belediyespor | 10 | 4 | 0 | 6 | 10:16 | -6 | 12 |
| 13 |
|
Diyarbekirspor | 10 | 3 | 2 | 5 | 11:12 | -1 | 11 |
| 14 |
|
Inegölspor | 10 | 3 | 2 | 5 | 13:18 | -5 | 11 |
| 15 |
|
Sarıyer SK | 10 | 3 | 1 | 6 | 11:18 | -7 | 10 |
| 16 |
|
Ergene Velimeşe | 10 | 3 | 1 | 6 | 9:22 | -13 | 10 |
| 17 |
|
Turgutluspor | 10 | 2 | 3 | 5 | 12:18 | -6 | 9 |
| 18 |
|
Niğde Anadolu FK | 10 | 1 | 1 | 8 | 4:26 | -22 | 4 |
| 19 |
|
Adıyamanspor | 10 | 1 | 0 | 9 | 9:20 | -11 | 3 |
| 20 |
|
Kahramanmaraşspor | 10 | 0 | 0 | 10 | 3:26 | -23 | 0 |
| Promotion | |
| Playoffs | |
| Relegation |
