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| 20/11/2021 | 10:00 | Etimesgut Belediyespor | - | Vanspor FK | 1:1 (1:0) | |
| 10:00 | Sarıyer SK | - | Hekimoğlu Trabzon | 0:1 (0:0) | ||
| 21/11/2021 | 10:00 | Bayburt İl Özel İdare | - | Inegölspor | 0:1 (0:1) | |
| 10:00 | Bodrumspor | - | Somaspor | 3:1 (2:0) | ||
| 10:00 | Çorum FK | - | Ankaraspor | 0:0 (0:0) | ||
| 10:00 | Kahramanmaraşspor | - | Adıyamanspor | 0:4 (0:1) | ||
| 10:00 | Serik Belediyespor | - | Afjet Afyonspor | 0:0 (0:0) | ||
| 10:00 | Sivas Belediyespor | - | Niğde Anadolu FK | 6:1 (3:0) | ||
| 10:00 | Turgutluspor | - | Diyarbekirspor | 2:1 (1:1) | ||
| 11:30 | Sakaryaspor | - | Ergene Velimeşe | 3:2 (3:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sakaryaspor | 14 | 9 | 5 | 0 | 27:5 | 22 | 32 |
| 2 |
|
Hekimoğlu Trabzon | 14 | 9 | 5 | 0 | 27:8 | 19 | 32 |
| 3 |
|
Sivas Belediyespor | 14 | 9 | 3 | 2 | 28:6 | 22 | 30 |
| 4 |
|
Çorum FK | 14 | 7 | 6 | 1 | 21:7 | 14 | 27 |
| 5 |
|
Bodrumspor | 14 | 8 | 2 | 4 | 25:11 | 14 | 26 |
| 6 |
|
Vanspor FK | 14 | 7 | 4 | 3 | 21:19 | 2 | 25 |
| 7 |
|
Bayburt İl Özel İdare | 14 | 7 | 3 | 4 | 19:13 | 6 | 24 |
| 8 |
|
Ankaraspor | 14 | 6 | 4 | 4 | 25:16 | 9 | 22 |
| 9 |
|
Afjet Afyonspor | 14 | 5 | 7 | 2 | 22:15 | 7 | 22 |
| 10 |
|
Somaspor | 14 | 6 | 4 | 4 | 22:19 | 3 | 22 |
| 11 |
|
Serik Belediyespor | 14 | 6 | 2 | 6 | 19:20 | -1 | 20 |
| 12 |
|
Etimesgut Belediyespor | 14 | 5 | 4 | 5 | 16:18 | -2 | 19 |
| 13 |
|
Inegölspor | 14 | 5 | 3 | 6 | 17:21 | -4 | 18 |
| 14 |
|
Diyarbekirspor | 14 | 4 | 3 | 7 | 15:17 | -2 | 15 |
| 15 |
|
Turgutluspor | 14 | 3 | 5 | 6 | 17:26 | -9 | 14 |
| 16 |
|
Sarıyer SK | 14 | 3 | 3 | 8 | 14:23 | -9 | 12 |
| 17 |
|
Ergene Velimeşe | 14 | 3 | 2 | 9 | 12:29 | -17 | 11 |
| 18 |
|
Adıyamanspor | 14 | 2 | 1 | 11 | 15:29 | -14 | 7 |
| 19 |
|
Niğde Anadolu FK | 14 | 1 | 2 | 11 | 9:38 | -29 | 5 |
| 20 |
|
Kahramanmaraşspor | 14 | 1 | 0 | 13 | 6:37 | -31 | 3 |
| Promotion | |
| Playoffs | |
| Relegation |
