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| 1st(1st leg) | Brøndby IF | - | Torpedo Moskva | 1:0 (0:0) | ||
| 2nd (2nd leg) | Torpedo Moskva | - | Brøndby IF | 2:4 (0:0, 1:0, 1:0) pso | ||
| 1st(1st leg): 06/03/1991 | 2nd (2nd leg): 20/03/1991 | Winner: Brøndby IF | ||||
| 1st(1st leg) | Atalanta | - | Inter | 0:0 (0:0) | ||
| 2nd (2nd leg) | Inter | - | Atalanta | 2:0 (0:0) | ||
| 1st(1st leg): 06/03/1991 | 2nd (2nd leg): 20/03/1991 | Winner: Inter | ||||
| 1st(1st leg) | Bologna FC | - | Sporting CP | 1:1 (0:0) | ||
| 2nd (2nd leg) | Sporting CP | - | Bologna FC | 2:0 (1:0) | ||
| 1st(1st leg): 06/03/1991 | 2nd (2nd leg): 20/03/1991 | Winner: Sporting CP | ||||
| 1st(1st leg) | AS Roma | - | RSC Anderlecht | 3:0 (1:0) | ||
| 2nd (2nd leg) | RSC Anderlecht | - | AS Roma | 2:3 (0:1) | ||
| 1st(1st leg): 06/03/1991 | 2nd (2nd leg): 20/03/1991 | Winner: AS Roma | ||||
