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| 1st(1st leg) | Stal Dniprodzerzhynsk | - | Dnipro Dnipropetrovsk | 0:3 (0:1) | ||
| 2nd (2nd leg) | Dnipro Dnipropetrovsk | - | Stal Dniprodzerzhynsk | 4:1 (1:0) | ||
| 1st(1st leg): 01/03/2016 15:00 | 2nd (2nd leg): 06/04/2016 17:00 | Winner: Dnipro Dnipropetrovsk | ||||
| 1st(1st leg) | FK Oleksandriya | - | Dinamo Kiev | 1:1 (1:0) | ||
| 2nd (2nd leg) | Dinamo Kiev | - | FK Oleksandriya | 0:1 (0:1) | ||
| 1st(1st leg): 01/03/2016 17:00 | 2nd (2nd leg): 06/04/2016 15:00 | Winner: FK Oleksandriya | ||||
| 1st(1st leg) | Volyn Lutsk | - | Zorya Lugansk | 1:1 (1:1) | ||
| 2nd (2nd leg) | Zorya Lugansk | - | Volyn Lutsk | 5:0 (1:0) | ||
| 1st(1st leg): 02/03/2016 17:00 | 2nd (2nd leg): 06/04/2016 12:00 | Winner: Zorya Lugansk | ||||
| 1st(1st leg) | Vorskla Poltava | - | Shakhtar Donetsk | 0:4 (0:1) | ||
| 2nd (2nd leg) | Shakhtar Donetsk | - | Vorskla Poltava | 1:2 (0:1) | ||
| 1st(1st leg): 02/03/2016 17:30 | 2nd (2nd leg): 27/03/2016 15:00 | Winner: Shakhtar Donetsk | ||||
