 |
 |
|
| 1st(1st leg) | Estudiantes de Mérida | - | Deportivo Táchira | 0:0 (0:0) | ||
| 2nd (2nd leg) | Deportivo Táchira | - | Estudiantes de Mérida | 3:1 (2:1) | ||
| 1st(1st leg): 03/11/2018 20:00 | 2nd (2nd leg): 07/11/2018 23:00 | Winner: Deportivo Táchira | ||||
| 1st(1st leg) | Zamora FC | - | Deportivo La Guaira | 1:0 (1:0) | ||
| 2nd (2nd leg) | Deportivo La Guaira | - | Zamora FC | 3:1 (0:1) | ||
| 1st(1st leg): 03/11/2018 23:00 | 2nd (2nd leg): 07/11/2018 20:00 | Winner: Deportivo La Guaira | ||||
| 1st(1st leg) | Trujillanos FC | - | Deportivo Lara | 2:1 (1:1) | ||
| 2nd (2nd leg) | Deportivo Lara | - | Trujillanos FC | 1:0 (0:0) | ||
| 1st(1st leg): 04/11/2018 20:00 | 2nd (2nd leg): 08/11/2018 20:00 | Winner: Deportivo Lara | ||||
| 1st(1st leg) | Caracas FC | - | Monagas | 2:2 (1:1) | ||
| 2nd (2nd leg) | Monagas | - | Caracas FC | 1:2 (0:1) | ||
| 1st(1st leg): 04/11/2018 23:00 | 2nd (2nd leg): 08/11/2018 23:00 | Winner: Caracas FC | ||||
