| Squad | Appearances | ||
| sorting |
| Name |  |
 |
 |
 |
 |
 |
 |
 |
 |
| Mikaël Silvestre | 2921' | 34 | 34 | - | 6 | 1 | 2 | - | - |
| Ruud van Nistelrooy | 2903' | 34 | 33 | 1 | 11 | 25 | 3 | - | - |
| Ryan Giggs | 2852' | 36 | 32 | 4 | 8 | 8 | - | - | - |
| Paul Scholes | 2741' | 33 | 31 | 2 | 6 | 14 | 4 | - | - |
| Ole Gunnar Solskjær | 2599' | 37 | 29 | 8 | 7 | 9 | 4 | - | - |
| Fabien Barthez | 2540' | 30 | 30 | - | 3 | - | 1 | - | - |
| David Beckham | 2516' | 31 | 27 | 4 | 2 | 6 | 5 | - | - |
| Rio Ferdinand | 2437' | 28 | 27 | 1 | - | - | 3 | - | - |
| John O'Shea | 2285' | 32 | 26 | 6 | 6 | - | - | - | - |
| Wes Brown | 1853' | 22 | 22 | - | 4 | - | 3 | - | - |
| Gary Neville | 1824' | 26 | 19 | 7 | 2 | - | 3 | - | - |
| Juan Sebastián Verón | 1761' | 25 | 21 | 4 | 9 | 2 | 1 | - | - |
| Roy Keane | 1673' | 21 | 19 | 2 | 2 | - | 4 | - | 1 |
| Phil Neville | 1666' | 25 | 19 | 6 | 8 | 1 | 7 | - | - |
| Laurent Blanc | 1423' | 19 | 15 | 4 | 1 | - | 2 | - | - |
| Nicky Butt | 1218' | 18 | 14 | 4 | 4 | - | 1 | - | - |
| Roy Carroll | 834' | 10 | 8 | 2 | - | - | - | - | - |
| Diego Forlán | 834' | 25 | 7 | 18 | 4 | 6 | 2 | - | - |
| Quinton Fortune | 507' | 9 | 5 | 4 | 2 | - | 1 | - | - |
| Ricardo | 46' | 1 | - | 1 | - | - | - | - | - |
| Kieran Richardson | 41' | 2 | - | 2 | - | - | - | - | - |
| Luke Chadwick | 27' | 1 | - | 1 | - | - | - | - | - |
| Lee Roche | 21' | 1 | - | 1 | - | - | - | - | - |
| Danny Pugh | 5' | 1 | - | 1 | - | - | - | - | - |
| David May | 2' | 1 | - | 1 | - | - | - | - | - |
| Michael Stewart | 1' | 1 | - | 1 | - | - | - | - | - |
| Jimmy Davis | - | - | - | - | - | - | - | - | - |
| Chris Eagles | - | - | - | - | - | - | - | - | - |
| Darren Fletcher | - | - | - | - | - | - | - | - | - |
| Colin Heath | - | - | - | - | - | - | - | - | - |
| Mark Lynch | - | - | - | - | - | - | - | - | - |
| Daniel Nardiello | - | - | - | - | - | - | - | - | - |
| Luke Steele | - | - | - | - | - | - | - | - | - |
| Paul Tierney | - | - | - | - | - | - | - | - | - |
| Mads Timm | - | - | - | - | - | - | - | - | - |
| Danny Webber | - | - | - | - | - | - | - | - | - |
| Ben Williams | - | - | - | - | - | - | - | - | - |
England