| Copa Sudamericana | M. | W | D | L | goals | |||
| at home | 1 | 1 | 0 | 0 | 3 | : | 1 | |
| Away | 1 | 1 | 0 | 0 | 4 | : | 1 | |
| ∑ | 2 | 2 | 0 | 0 | 7 | : | 2 | |
| Primera División | M. | W | D | L | goals | |||
| at home | 23 | 8 | 6 | 9 | 23 | : | 27 | |
| Away | 24 | 4 | 9 | 11 | 27 | : | 45 | |
| ∑ | 47 | 12 | 15 | 20 | 50 | : | 72 | |
| Copa de la Superliga | M. | W | D | L | goals | |||
| at home | 1 | 0 | 0 | 1 | 1 | : | 2 | |
| Away | 1 | 0 | 0 | 1 | 1 | : | 3 | |
| ∑ | 2 | 0 | 0 | 2 | 2 | : | 5 | |
| overall | M. | W | D | L | goals | |||
| at home | 25 | 9 | 6 | 10 | 27 | : | 30 | |
| Away | 26 | 5 | 9 | 12 | 32 | : | 49 | |
| Neutral Place | 0 | 0 | 0 | 0 | 0 | : | 0 | |
| ∑ | 51 | 14 | 15 | 22 | 59 | : | 79 | |
| Copa Sudamericana | |||||
| 2003 | 1. Round | Vélez Sarsfield | - | Colón de Santa Fe | 1:4 (0:1) |
| 2003 | 1. Round | Colón de Santa Fe | - | Vélez Sarsfield | 3:1 (1:0) |
| Copa de la Superliga | |||||
| 2023 | 14. Round | Vélez Sarsfield | - | Colón de Santa Fe | 3:1 (2:0) |
| 2022 | 14. Round | Colón de Santa Fe | - | Vélez Sarsfield | 1:2 (0:1) |
|
For games that were decided on penalties the score after 120 minutes will be included in the ranking |
Argentina 
![Colón de Santa Fe [U20]](https://s.hs-data.com/bilder/wappen/mini/26341.gif?fallback=png "Colón de Santa Fe [U20]"){kind=small}
![Colón de Santa Fe [U16]](https://s.hs-data.com/bilder/wappen/mini/29635.gif?fallback=png "Colón de Santa Fe [U16]"){kind=small}
