Championship   M. W D L goals
  at home 13 11 1 1 35 : 12
  Away 13 4 4 5 14 : 16
  26 15 5 6 49 : 28
FA Cup   M. W D L goals
  at home 1 1 0 0 5 : 1
  Away 2 1 1 0 2 : 1
  3 2 1 0 7 : 2
League One   M. W D L goals
  at home 5 3 0 2 8 : 4
  Away 5 0 1 4 5 : 11
  10 3 1 6 13 : 15
League Two   M. W D L goals
  at home 3 2 0 1 6 : 5
  Away 3 0 3 0 4 : 4
  6 2 3 1 10 : 9
overall   M. W D L goals
  at home 22 17 1 4 54 : 22
  Away 23 5 9 9 25 : 32
  Neutral Place 0 0 0 0 0 : 0
  45 22 10 13 79 : 54
Championship
1956/1957 8. Round Leyton Orient - Port Vale FC 3:2
1956/1957 4. Round Port Vale FC - Leyton Orient 1:2
1928/1929 8. Round Clapton Orient - Port Vale FC 1:0
1928/1929 3. Round Port Vale FC - Clapton Orient 3:0
1927/1928 9. Round Port Vale FC - Clapton Orient 0:0
1927/1928 5. Round Clapton Orient - Port Vale FC 0:1
1926/1927 5. Round Port Vale FC - Clapton Orient 3:0
1926/1927 5. Round Clapton Orient - Port Vale FC 1:2
1925/1926 6. Round Port Vale FC - Clapton Orient 4:2
1925/1926 1. Round Clapton Orient - Port Vale FC 1:2
1924/1925 8. Round Port Vale FC - Clapton Orient 4:2
1924/1925 4. Round Clapton Orient - Port Vale FC 3:1
1923/1924 4. Round Port Vale FC - Clapton Orient 1:0
1923/1924 4. Round Clapton Orient - Port Vale FC 1:1
1922/1923 2. Round Port Vale FC - Clapton Orient 3:1
1922/1923 2. Round Clapton Orient - Port Vale FC 0:0
1921/1922 2. Round Clapton Orient - Port Vale FC 2:0
1921/1922 1. Round Port Vale FC - Clapton Orient 3:0
1920/1921 8. Round Clapton Orient - Port Vale FC 0:0
1920/1921 5. Round Port Vale FC - Clapton Orient 4:0
1919/1920 3. Round Port Vale FC - Clapton Orient 4:2
1919/1920 3. Round Clapton Orient - Port Vale FC 2:1
1906/1907 7. Round Clapton Orient - Port Vale FC 1:1
1906/1907 3. Round Port Vale FC - Clapton Orient 3:2
1905/1906 6. Round Clapton Orient - Port Vale FC 1:3
1905/1906 1. Round Port Vale FC - Clapton Orient 2:1
FA Cup
1953/1954 Quarter-finals Leyton Orient - Port Vale FC 0:1
1926/1927 3. Round Port Vale FC - Clapton Orient 5:1
1926/1927 3. Round Clapton Orient - Port Vale FC 1:1
League One
2023/2024 38. Round Leyton Orient - Port Vale FC 0:0 (0:0)
2023/2024 18. Round Port Vale FC - Leyton Orient 0:1 (0:0)
2014/2015 39. Round Leyton Orient - Port Vale FC 3:1 (0:1)
2014/2015 15. Round Port Vale FC - Leyton Orient 3:0 (0:0)
2013/2014 36. Round Port Vale FC - Leyton Orient 0:2 (0:1)
2013/2014 7. Round Leyton Orient - Port Vale FC 3:2 (2:1)
2007/2008 41. Round Port Vale FC - Leyton Orient 2:1 (0:1)
2007/2008 12. Round Leyton Orient - Port Vale FC 3:1 (0:1)
2006/2007 31. Round Leyton Orient - Port Vale FC 2:1 (0:1)
2006/2007 1. Round Port Vale FC - Leyton Orient 3:0 (1:0)
League Two
2021/2022 28. Round Leyton Orient - Port Vale FC 0:0 (0:0)
2021/2022 10. Round Port Vale FC - Leyton Orient 3:2 (1:0)
2020/2021 30. Round Leyton Orient - Port Vale FC 1:1 (0:0)
2020/2021 15. Round Port Vale FC - Leyton Orient 2:3 (1:2)
2019/2020 28. Round Port Vale FC - Leyton Orient 1:0 (0:0)
2019/2020 11. Round Leyton Orient - Port Vale FC 3:3 (1:2)

For games that were decided on penalties the score after 120 minutes will be included in the ranking