Serie A   M. W D L goals
  at home 8 2 3 3 8 : 13
  Away 8 0 2 6 5 : 15
  16 2 5 9 13 : 28
Serie B   M. W D L goals
  at home 4 4 0 0 9 : 4
  Away 4 1 1 2 1 : 3
  8 5 1 2 10 : 7
Coppa Italia   M. W D L goals
  at home 1 0 0 1 0 : 2
  Away 2 0 0 2 2 : 7
  3 0 0 3 2 : 9
overall   M. W D L goals
  at home 13 6 3 4 17 : 19
  Away 14 1 3 10 8 : 25
  Neutral Place 0 0 0 0 0 : 0
  27 7 6 14 25 : 44
Serie A
2023/2024 22. Round Genoa CFC - US Lecce 2:1 (0:1)
2023/2024 5. Round US Lecce - Genoa CFC 1:0 (0:0)
2019/2020 34. Round Genoa CFC - US Lecce 2:1 (1:0)
2019/2020 15. Round US Lecce - Genoa CFC 2:2 (0:2)
2011/2012 26. Round US Lecce - Genoa CFC 2:2 (0:1)
2011/2012 7. Round Genoa CFC - US Lecce 0:0 (0:0)
2010/2011 34. Round Genoa CFC - US Lecce 4:2 (2:2)
2010/2011 15. Round US Lecce - Genoa CFC 1:3 (1:0)
2008/2009 38. Round Genoa CFC - US Lecce 4:1 (1:1)
2008/2009 19. Round US Lecce - Genoa CFC 0:2 (0:0)
1993/1994 25. Round Genoa CFC - US Lecce 2:0 (2:0)
1993/1994 8. Round US Lecce - Genoa CFC 0:0 (0:0)
1990/1991 21. Round US Lecce - Genoa CFC 0:3 (0:2)
1990/1991 4. Round Genoa CFC - US Lecce 0:0 (0:0)
1989/1990 18. Round US Lecce - Genoa CFC 2:1 (2:0)
1989/1990 1. Round Genoa CFC - US Lecce 1:0 (1:0)
Serie B
2006/2007 26. Round Genoa CFC - US Lecce 1:0 (0:0)
2006/2007 5. Round US Lecce - Genoa CFC 3:2 (2:2)
2002/2003 28. Round US Lecce - Genoa CFC 2:1 (0:0)
2002/2003 9. Round Genoa CFC - US Lecce 0:0 (0:0)
1998/1999 21. Round US Lecce - Genoa CFC 3:1 (3:0)
1998/1999 2. Round Genoa CFC - US Lecce 0:1 (0:1)
1996/1997 25. Round US Lecce - Genoa CFC 1:0
1996/1997 6. Round Genoa CFC - US Lecce 2:0
Coppa Italia
2018/2019 3. Round Genoa CFC - US Lecce 4:0 (4:0)
2016/2017 3. Round Genoa CFC - US Lecce 3:2 (0:0)
1996/1997 1. Round US Lecce - Genoa CFC 0:2 dec.

For games that were decided on penalties the score after 120 minutes will be included in the ranking