4. Round | 21/02/2021 | Club Nacional | - | Libertad | 0:3 | ||||
2. Round | 24/02/2021 | Guaireña FC | - | Libertad | 1:0 | ||||
5. Round | 01/03/2021 | Libertad | - | River Plate | 2:1 | ||||
6. Round | 05/03/2021 | 12 de Octubre de Itauguá | - | Libertad | 2:1 | ||||
8. Round | 13/03/2021 | Sol de América | - | Libertad | 0:2 | ||||
13. Round | 26/04/2021 | Libertad | - | Club Nacional | 1:1 | ||||
18. Round | 29/05/2021 | Sportivo Luqueño | - | Libertad | 1:3 |