1. Round | 17/02/2021 | Vida | - | Platense | 2:2 | ||||
2. Round | 21/02/2021 | Honduras Progreso | - | Vida | 0:0 | ||||
3. Round | 24/02/2021 | Vida | - | Marathón | 0:1 | ||||
4. Round | 27/02/2021 | Vida | - | Real Sociedad | 2:2 | ||||
5. Round | 05/03/2021 | Real España | - | Vida | 0:0 | ||||
6. Round | 07/03/2021 | Platense | - | Vida | 2:2 | ||||
7. Round | 10/03/2021 | Vida | - | Honduras Progreso | 1:1 | ||||
8. Round | 17/03/2021 | Marathón | - | Vida | 1:2 | ||||
9. Round | 21/03/2021 | Real Sociedad | - | Vida | 2:4 | ||||
10. Round | 04/04/2021 | Vida | - | Real España | 2:3 | ||||
11. Round | 11/04/2021 | Vida | - | Olimpia | 0:3 | ||||
12. Round | 18/04/2021 | Real de Minas | - | Vida | 2:2 | ||||
13. Round | 22/04/2021 | Vida | - | Motagua | 1:1 |