| Recalificación | 24/11/2021 | TM Fútbol Club | - | Mineros de Zacatecas | 2:1 |  |
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| Quarter-finals | 01/12/2021 | TM Fútbol Club | - | Atlético Morelia | 2:2 | ||||
| Quarter-finals | 04/12/2021 | Atlético Morelia | - | TM Fútbol Club | 0:2 | ||||
| Semi-finals | 09/12/2021 | TM Fútbol Club | - | Dorados de Sinaloa | 1:0 | |
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| Semi-finals | 12/12/2021 | Dorados de Sinaloa | - | TM Fútbol Club | 0:1 | |
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| Final | 16/12/2021 | TM Fútbol Club | - | Atlante | 0:0 | ||||
| Final | 19/12/2021 | Atlante | - | TM Fútbol Club | 3:0 | |
Mexico