6. Round | 27/08/2021 | KV Kortrijk | - | KV Mechelen | 2:2 | ||||
12. Round | 23/10/2021 | KV Mechelen | - | SV Zulte Waregem | 2:2 | ||||
13. Round | 29/10/2021 | KV Oostende | - | KV Mechelen | 2:4 | ||||
14. Round | 06/11/2021 | KV Mechelen | - | Sint-Truidense VV | 0:1 | ||||
15. Round | 19/11/2021 | KV Mechelen | - | Club Brugge KV | 2:1 | ||||
16. Round | 27/11/2021 | Cercle Brugge | - | KV Mechelen | 3:1 | ||||
17. Round | 05/12/2021 | KV Mechelen | - | KRC Genk | 1:1 | ||||
18. Round | 12/12/2021 | Union Saint-Gilloise | - | KV Mechelen | 2:0 | ||||
19. Round | 15/12/2021 | KV Mechelen | - | KAA Gent | 4:3 | ||||
20. Round | 18/12/2021 | SV Zulte Waregem | - | KV Mechelen | 3:2 |