2. Round | 11/02/2022 | Sportivo Ameliano | - | Resistencia SC | 1:4 | ||||
6. Round | 12/03/2022 | Sol de América | - | Resistencia SC | 1:1 | ||||
10. Round | 18/04/2022 | Resistencia SC | - | General Caballero DJLM | 2:1 | ||||
11. Round | 21/04/2022 | Libertad | - | Resistencia SC | 2:2 | ||||
13. Round | 29/04/2022 | Resistencia SC | - | Sportivo Ameliano | 3:0 | ||||
14. Round | 06/05/2022 | Club Nacional | - | Resistencia SC | 1:2 | ||||
19. Round | 19/06/2022 | Club Olimpia | - | Resistencia SC | 6:1 | ||||
21. Round | 25/06/2022 | General Caballero DJLM | - | Resistencia SC | 2:1 |