2. Round | 10/02/2018 | Libertad | - | Guaraní | 2:0 | ||||
4. Round | 26/02/2018 | Club Olimpia | - | Guaraní | 5:2 | ||||
5. Round | 05/03/2018 | Guaraní | - | Independiente CG | 0:1 | ||||
6. Round | 11/03/2018 | General Díaz | - | Guaraní | 0:3 | ||||
7. Round | 15/03/2018 | Guaraní | - | Sportivo Luqueño | 1:4 | ||||
12. Round | 17/04/2018 | Sol de América | - | Guaraní | 0:0 | ||||
16. Round | 08/05/2018 | Independiente CG | - | Guaraní | 2:1 | ||||
17. Round | 14/05/2018 | Guaraní | - | General Díaz | 2:2 | ||||
19. Round | 26/05/2018 | Club Nacional | - | Guaraní | 3:0 | ||||
21. Round | 06/06/2018 | Cerro Porteño | - | Guaraní | 2:1 |