4. Round | 07/02/2022 | Club León [U20] | - | Cruz Azul [U20] | 2:1 | ||||
6. Round | 19/02/2022 | Club León [U20] | - | Deportivo Guadalajara [U20] | 3:0 | ||||
7. Round | 25/02/2022 | Club Necaxa [U20] | - | Club León [U20] | 0:3 | ||||
12. Round | 03/04/2022 | Club León [U20] | - | Gallos Blancos [U20] | 2:1 | ||||
13. Round | 09/04/2022 | Atlético San Luis [U20] | - | Club León [U20] | 1:1 | ||||
15. Round | 20/04/2022 | CF América [U20] | - | Club León [U20] | 2:1 | ||||
17. Round | 01/05/2022 | Club León [U20] | - | Deportivo Toluca [U20] | 3:1 |