| 17. Round | 18/02/2006 | Vysočina Jihlava | - | 1. FC Brno | 0:0 |  |
|||
| 18. Round | 25/02/2006 | 1. FC Brno | - | AC Sparta Praha | 1:1 | ||||
| 21. Round | 19/03/2006 | FK Teplice | - | 1. FC Brno | 1:1 | ||||
| 22. Round | 26/03/2006 | 1. FC Brno | - | 1. FC Slovácko | 0:0 | |
|||
| 24. Round | 09/04/2006 | 1. FC Brno | - | Sigma Olomouc | 1:1 | ||||
| 20. Round | 20/04/2006 | 1. FC Brno | - | Chmel Blsany | 1:0 | |
|||
| 26. Round | 23/04/2006 | 1. FC Brno | - | Tescoma Zlín | 1:1 | ||||
| 27. Round | 26/04/2006 | Viktoria Plzeň | - | 1. FC Brno | 2:1 | ||||
| 28. Round | 30/04/2006 | 1. FC Brno | - | FK Mladá Boleslav | 4:2 | ||||
| 19. Round | 03/05/2006 | Baník Ostrava | - | 1. FC Brno | 1:1 |  |
|||
| 25. Round | 06/05/2006 | Slavia Praha | - | 1. FC Brno | 3:1 | ||||
| 29. Round | 10/05/2006 | FK SIAD Most | - | 1. FC Brno | 3:3 | ||||
| 30. Round | 13/05/2006 | 1. FC Brno | - | FK Marila Příbram | 1:0 |
Czech Republic