1. Round | 18/07/2018 | Club Nacional | - | Club Olimpia | 1:2 | ||||
2. Round | 23/07/2018 | Independiente CG | - | Club Nacional | 2:2 | ||||
3. Round | 29/07/2018 | Club Nacional | - | General Díaz | 1:1 | ||||
4. Round | 05/08/2018 | Guaraní | - | Club Nacional | 1:1 | ||||
5. Round | 11/08/2018 | Club Nacional | - | Deportivo Santaní | 3:1 | ||||
6. Round | 21/08/2018 | Libertad | - | Club Nacional | 1:0 | ||||
7. Round | 25/08/2018 | Club Nacional | - | Sportivo Luqueño | 3:1 | ||||
8. Round | 01/09/2018 | Sol de América | - | Club Nacional | 1:1 | ||||
10. Round | 16/09/2018 | 3 de Febrero | - | Club Nacional | 1:3 | ||||
13. Round | 07/10/2018 | Club Nacional | - | Independiente CG | 0:3 | ||||
16. Round | 29/10/2018 | Deportivo Santaní | - | Club Nacional | 3:0 | ||||
17. Round | 04/11/2018 | Club Nacional | - | Libertad | 1:2 |