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| 1st(1st leg) | WIT Georgia | - | Spartak Tskhinvali | 2:1 (1:0) | ||
| 2nd (2nd leg) | Spartak Tskhinvali | - | WIT Georgia | 0:1 (0:0) | ||
| 1st(1st leg): 01/12/2010 10:00 | 2nd (2nd leg): 15/12/2010 09:00 | Winner: WIT Georgia | ||||
| 1st(1st leg) | Sioni Bolnisi | - | Torpedo Kutaisi | 0:1 (0:0) | ||
| 2nd (2nd leg) | Torpedo Kutaisi | - | Sioni Bolnisi | 0:0 (0:0) | ||
| 1st(1st leg): 01/12/2010 10:00 | 2nd (2nd leg): 16/12/2010 13:00 | Winner: Torpedo Kutaisi | ||||
| 1st(1st leg) | FC Gagra | - | Dinamo Tbilisi | 1:2 (1:2) | ||
| 2nd (2nd leg) | Dinamo Tbilisi | - | FC Gagra | 2:4 (0:1, 1:2, 1:2) pso | ||
| 1st(1st leg): 01/12/2010 10:00 | 2nd (2nd leg): 16/12/2010 09:00 | Winner: FC Gagra | ||||
| 1st(1st leg) | FC Zestafoni | - | FC Olimpi Rustavi | 3:0 (1:0) | ||
| 2nd (2nd leg) | FC Olimpi Rustavi | - | FC Zestafoni | 0:0 (0:0) | ||
| 1st(1st leg): 01/12/2010 14:00 | 2nd (2nd leg): 15/12/2010 09:00 | Winner: FC Zestafoni | ||||
