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| 28/11/2021 | 13:00 | Kauno Žalgiris | - | FK Banga Gargždai | 0:1 (0:0) | |
| 13:00 | FK Panevėžys | - | Hegelmann Litauen | 2:2 (2:1) | ||
| 13:00 | FK Sūduva | - | DFK Dainava | 0:1 (0:0) | ||
| 13:00 | FK Nevėžis | - | FK Riteriai | 0:6 (0:4) | ||
| 13:00 | FK Žalgiris | - | FC Džiugas | 3:2 (1:1) |
| » Tables | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FK Žalgiris | 36 | 23 | 10 | 3 | 76:28 | 48 | 79 |
| 2 |
|
FK Sūduva | 36 | 21 | 7 | 8 | 64:33 | 31 | 70 |
| 3 |
|
Kauno Žalgiris | 36 | 18 | 9 | 9 | 55:39 | 16 | 63 |
| 4 |
|
FK Panevėžys | 36 | 16 | 12 | 8 | 55:40 | 15 | 60 |
| 5 |
|
Hegelmann Litauen | 36 | 14 | 11 | 11 | 53:38 | 15 | 53 |
| 6 |
|
FK Riteriai | 36 | 10 | 16 | 10 | 49:37 | 12 | 46 |
| 7 |
|
FK Banga Gargždai | 36 | 10 | 6 | 20 | 40:71 | -31 | 36 |
| 8 |
|
FC Džiugas | 36 | 8 | 12 | 16 | 47:60 | -13 | 36 |
| 9 |
|
DFK Dainava | 36 | 9 | 11 | 16 | 39:56 | -17 | 35 |
| 10 |
|
FK Nevėžis | 36 | 2 | 4 | 30 | 15:91 | -76 | 10 |
| Champions League Quali. | |
| Relegation |
