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| 1st(1st leg) | Puebla FC II | - | Deportivo Guadalajara II | 1:0 | ||
| 2nd (2nd leg) | Deportivo Guadalajara II | - | Puebla FC II | 0:1 | ||
| 1st(1st leg): 03/05/2018 17:00 | 2nd (2nd leg): 06/05/2018 17:00 | Winner: Puebla FC II | ||||
| 1st(1st leg) | Gallos Blancos II | - | Club Necaxa II | 1:0 | ||
| 2nd (2nd leg) | Club Necaxa II | - | Gallos Blancos II | 4:0 | ||
| 1st(1st leg): 03/05/2018 23:00 | 2nd (2nd leg): 06/05/2018 17:00 | Winner: Club Necaxa II | ||||
