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| 1st(1st leg) | CF Pachuca | - | Santos Laguna | 1:2 | ||
| 2nd (2nd leg) | Santos Laguna | - | CF Pachuca | 2:2 | ||
| 1st(1st leg): 17/05/2018 01:00 | 2nd (2nd leg): 19/05/2018 16:00 | Winner: Santos Laguna | ||||
|
|
|
| 1st(1st leg) | CF Pachuca | - | Santos Laguna | 1:2 | ||
| 2nd (2nd leg) | Santos Laguna | - | CF Pachuca | 2:2 | ||
| 1st(1st leg): 17/05/2018 01:00 | 2nd (2nd leg): 19/05/2018 16:00 | Winner: Santos Laguna | ||||
