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| 1st(1st leg) | Deportivo Toluca | - | Atlas Guadalajara | 0:1 | ||
| 2nd (2nd leg) | Atlas Guadalajara | - | Deportivo Toluca | 3:1 | ||
| 1st(1st leg): 23/11/2016 15:00 | 2nd (2nd leg): 26/11/2016 15:00 | Winner: Atlas Guadalajara | ||||
| 1st(1st leg) | Club León | - | Monarcas Morelia | 1:1 | ||
| 2nd (2nd leg) | Monarcas Morelia | - | Club León | 2:2 | ||
| 1st(1st leg): 23/11/2016 16:00 | 2nd (2nd leg): 26/11/2016 16:00 | Winner: Club León | ||||
| 1st(1st leg) | UANL Tigres | - | CF Monterrey | 1:0 | ||
| 2nd (2nd leg) | CF Monterrey | - | UANL Tigres | 1:0 | ||
| 1st(1st leg): 23/11/2016 17:15 | 2nd (2nd leg): 26/11/2016 15:00 | |||||
| 1st(1st leg) | Deportivo Guadalajara | - | Santos Laguna | 1:2 | ||
| 2nd (2nd leg) | Santos Laguna | - | Deportivo Guadalajara | 3:0 | ||
| 1st(1st leg): 24/11/2016 16:00 | 2nd (2nd leg): 27/11/2016 17:00 | Winner: Santos Laguna | ||||
