Serie A   M. W D L goals
  at home 10 5 5 0 19 : 9
  Away 10 1 3 6 6 : 19
  20 6 8 6 25 : 28
Coppa Italia   M. W D L goals
  at home 2 1 1 0 3 : 2
  Away 1 1 0 0 1 : 0
  3 2 1 0 4 : 2
overall   M. W D L goals
  at home 12 6 6 0 22 : 11
  Away 11 2 3 6 7 : 19
  Neutral Place 0 0 0 0 0 : 0
  23 8 9 6 29 : 30
Serie A
2012/2013 25. Round AC Siena - Lazio Roma 3:0 (2:0)
2012/2013 6. Round Lazio Roma - AC Siena 2:1 (2:0)
2011/2012 36. Round Lazio Roma - AC Siena 1:1 (0:1)
2011/2012 17. Round AC Siena - Lazio Roma 4:0 (3:0)
2009/2010 30. Round Lazio Roma - AC Siena 2:0 (1:0)
2009/2010 11. Round AC Siena - Lazio Roma 1:1 (1:1)
2008/2009 30. Round AC Siena - Lazio Roma 2:0 (1:0)
2008/2009 11. Round Lazio Roma - AC Siena 3:0 (0:0)
2007/2008 33. Round Lazio Roma - AC Siena 1:1 (1:0)
2007/2008 14. Round AC Siena - Lazio Roma 1:1 (1:1)
2006/2007 38. Round AC Siena - Lazio Roma 2:1 (1:0)
2006/2007 19. Round Lazio Roma - AC Siena 1:1 (0:0)
2005/2006 33. Round AC Siena - Lazio Roma 2:3 (2:2)
2005/2006 14. Round Lazio Roma - AC Siena 3:2 (1:0)
2004/2005 29. Round AC Siena - Lazio Roma 1:0 (0:0)
2004/2005 10. Round Lazio Roma - AC Siena 1:1 (0:0)
2003/2004 28. Round Lazio Roma - AC Siena 5:2 (2:2)
2003/2004 11. Round AC Siena - Lazio Roma 3:0 (2:0)
1945/1946 South 18. Round AC Siena - Lazio Roma 0:0
1945/1946 South 7. Round Lazio Roma - AC Siena 0:0
Coppa Italia
2012/2013 Round of 16 Lazio Roma - AC Siena 4:1 (0:0, 1:1, 1:1) pso
2001/2002 Round of 16 AC Siena - Lazio Roma 0:1 (0:1)
2001/2002 Round of 16 Lazio Roma - AC Siena 2:1 (2:1)

For games that were decided on penalties the score after 120 minutes will be included in the ranking