Primera División   M. W D L goals
  at home 24 7 7 10 31 : 40
  Away 20 5 6 9 31 : 36
  44 12 13 19 62 : 76
Cup   M. W D L goals
  Away 2 0 0 2 1 : 4
  2 0 0 2 1 : 4
overall   M. W D L goals
  at home 24 7 7 10 31 : 40
  Away 22 5 6 11 32 : 40
  Neutral Place 0 0 0 0 0 : 0
  46 12 13 21 63 : 80
Primera División
2024 Apertura 8. Round Defensor Sporting - River Plate 2:1 (1:0)
2023 Clausura 13. Round Defensor Sporting - River Plate 0:1 (0:0)
2023 Intermedio Group A River Plate - Defensor Sporting 1:1 (0:1)
2023 Apertura 13. Round River Plate - Defensor Sporting 0:4 (0:3)
2022 Clausura 7. Round River Plate - Defensor Sporting 0:1 (0:1)
2022 Intermedio Group B River Plate - Defensor Sporting 1:1 (0:0)
2022 Apertura 7. Round Defensor Sporting - River Plate 3:2 (2:0)
2020 Clausura 3. Round Defensor Sporting - River Plate 0:2 (0:0)
2020 Intermedio Group B River Plate - Defensor Sporting 1:1 (1:1)
2020 Apertura 3. Round River Plate - Defensor Sporting 1:1 (0:0)
2019 Clausura 12. Round River Plate - Defensor Sporting 1:0 (1:0)
2019 Intermedio 3. Round River Plate - Defensor Sporting 2:1 (1:1)
2019 Apertura 12. Round Defensor Sporting - River Plate 1:1 (0:0)
2018 Clausura 10. Round River Plate - Defensor Sporting 3:2 (1:1)
2018 Intermedio 2. Round River Plate - Defensor Sporting 1:0 (0:0)
2018 Apertura 10. Round Defensor Sporting - River Plate 5:2 (2:1)
2017 Clausura 7. Round Defensor Sporting - River Plate 2:1 (0:1)
2017 Apertura 7. Round River Plate - Defensor Sporting 0:1 (0:0)
2016 4. Round River Plate - Defensor Sporting 0:5 (0:2)
2015/2016 Clausura 14. Round River Plate - Defensor Sporting 1:2 (1:0)
2015/2016 Apertura 14. Round Defensor Sporting - River Plate 1:2 (1:0)
2014/2015 Clausura 11. Round River Plate - Defensor Sporting 1:2 (0:0)
2014/2015 Apertura 11. Round Defensor Sporting - River Plate 0:2 (0:2)
2013/2014 Clausura 15. Round River Plate - Defensor Sporting 3:1 (2:0)
2013/2014 Apertura 15. Round Defensor Sporting - River Plate 1:1 (0:0)
2012/2013 Clausura 13. Round Defensor Sporting - River Plate 2:2 (1:1)
2012/2013 Apertura 13. Round River Plate - Defensor Sporting 1:1 (0:0)
2011/2012 Clausura 15. Round River Plate - Defensor Sporting 2:1 (1:1)
2011/2012 Apertura 15. Round Defensor Sporting - River Plate 0:2 (0:2)
2010/2011 Clausura 1. Round Defensor Sporting - River Plate 4:1 (1:1)
2010/2011 Apertura 1. Round River Plate - Defensor Sporting 1:1 (1:1)
2009/2010 Clausura 13. Round Defensor Sporting - River Plate 1:1 (1:0)
2009/2010 Apertura 13. Round River Plate - Defensor Sporting 1:2 (0:0)
2009 Liguilla 1. Round River Plate - Defensor Sporting 0:3 (0:2)
2008/2009 Clausura 4. Round Defensor Sporting - River Plate 3:2 (2:1)
2008/2009 Apertura 5. Round River Plate - Defensor Sporting 1:3
2008 Liguilla 5. Round Defensor Sporting - River Plate 1:0
2007/2008 Clausura 12. Round Defensor Sporting - River Plate 4:3
2007/2008 Apertura 12. Round River Plate - Defensor Sporting 5:1
2006/2007 Clausura 6. Round River Plate - Defensor Sporting 2:3
2006/2007 Apertura 6. Round Defensor Sporting - River Plate 2:2
2005/2006 Clausura 17. Round Defensor Sporting - River Plate 1:0
2005/2006 Apertura 17. Round River Plate - Defensor Sporting 2:2
2003 Clausura 10. Round Defensor Sporting - River Plate 3:3
Cup
2023 Semi-finals Defensor Sporting - River Plate 2:1
2022 Round of 16 Defensor Sporting - River Plate 2:0 (1:0)

For games that were decided on penalties the score after 120 minutes will be included in the ranking