13. Round | 30/04/2022 | General Caballero DJLM | - | Libertad | 0:1 | ||||
14. Round | 08/05/2022 | Libertad | - | Club Olimpia | 1:0 | ||||
15. Round | 11/05/2022 | Libertad | - | Tacuary | 3:0 | ||||
16. Round | 15/05/2022 | Sportivo Ameliano | - | Libertad | 1:3 | ||||
17. Round | 23/05/2022 | Libertad | - | Club Nacional | 1:0 | ||||
18. Round | 14/06/2022 | Guaraní | - | Libertad | 1:1 | ||||
19. Round | 18/06/2022 | Libertad | - | Guaireña FC | 2:0 | ||||
22. Round | 03/07/2022 | Resistencia SC | - | Libertad | 0:4 |