16. Round | 12/01/2022 | PAOK Saloniki | - | Panetolikos | 2:0 | ||||
18. Round | 16/01/2022 | AEK Athen | - | Panetolikos | 1:2 | ||||
20. Round | 30/01/2022 | Panetolikos | - | Aris Saloniki | 0:2 | ||||
21. Round | 02/02/2022 | Olympiakos Piraeus | - | Panetolikos | 3:1 | ||||
22. Round | 05/02/2022 | Panetolikos | - | PAS Giannina | 0:1 | ||||
24. Round | 19/02/2022 | Panetolikos | - | Panathinaikos | 1:0 | ||||
25. Round | 26/02/2022 | Panetolikos | - | Volos NFC | 0:0 | ||||
26. Round | 06/03/2022 | Ionikos Nikea | - | Panetolikos | 1:2 |