1. Round 08/08/2021 ADO Den Haag - Jong Ajax 2:0
2. Round 16/08/2021 Jong Ajax - FC Dordrecht 1:2
3. Round 20/08/2021 FC Den Bosch - Jong Ajax 2:3 yellow card
4. Round 27/08/2021 Jong Ajax - SBV Excelsior 1:2 yellow card
6. Round 10/09/2021 Jong PSV - Jong Ajax 3:1 yellow card
5. Round 13/09/2021 Jong Ajax - NAC Breda 6:3
7. Round 17/09/2021 Almere City FC - Jong Ajax 2:4
8. Round 27/09/2021 Jong Ajax - MVV 3:1
9. Round 01/10/2021 Helmond Sport - Jong Ajax 3:1 yellow card
10. Round 18/10/2021 AZ Alkmaar (J) - Jong Ajax 1:1
12. Round 22/10/2021 FC Eindhoven - Jong Ajax 1:3
13. Round 01/11/2021 Jong Ajax - Telstar 3:0
16. Round 19/11/2021 Jong Ajax - FC Volendam 4:4
15. Round 22/11/2021 Jong Ajax - Roda JC Kerkrade 2:1
17. Round 26/11/2021 De Graafschap - Jong Ajax 1:3
19. Round 10/12/2021 TOP Oss - Jong Ajax 1:1
20. Round 20/12/2021 Jong Ajax - Helmond Sport 1:1
21. Round 10/01/2022 FC Utrecht (J) - Jong Ajax 0:2
22. Round 17/01/2022 Jong Ajax - FC Den Bosch 2:1
23. Round 23/01/2022 Telstar - Jong Ajax 1:0
25. Round 04/02/2022 Jong Ajax - AZ Alkmaar (J) 2:1
24. Round 07/02/2022 Jong Ajax - Jong PSV 2:0
26. Round 11/02/2022 SBV Excelsior - Jong Ajax 6:2
28. Round 25/02/2022 FC Emmen - Jong Ajax 2:1
29. Round 07/03/2022 Jong Ajax - ADO Den Haag 6:3
30. Round 11/03/2022 FC Dordrecht - Jong Ajax 3:3 yellow card
31. Round 18/03/2022 Jong Ajax - FC Eindhoven 2:2
33. Round 01/04/2022 NAC Breda - Jong Ajax 0:0
32. Round 04/04/2022 Jong Ajax - TOP Oss 4:1 yellow card
34. Round 08/04/2022 Roda JC Kerkrade - Jong Ajax 2:2
35. Round 16/04/2022 FC Volendam - Jong Ajax 3:1
36. Round 25/04/2022 Jong Ajax - VVV-Venlo 6:1
37. Round 29/04/2022 MVV - Jong Ajax 1:0 yellow card
38. Round 06/05/2022 Jong Ajax - De Graafschap 1:1