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| 1st(1st leg) | Erzeni Shijak | - | FK Kukësi | 1:4 (0:2) | ||
| 2nd (2nd leg) | FK Kukësi | - | Erzeni Shijak | 5:1 (3:0) | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: FK Kukësi | ||||
| 1st(1st leg) | KS Besëlidhja Lezhë | - | KF Skënderbeu | 0:1 (0:1) | ||
| 2nd (2nd leg) | KF Skënderbeu | - | KS Besëlidhja Lezhë | 3:1 (1:1) | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: KF Skënderbeu | ||||
| 1st(1st leg) | KS Kamza | - | KF Teuta Durrës | 1:1 (1:1) | ||
| 2nd (2nd leg) | KF Teuta Durrës | - | KS Kamza | 4:0 (1:0) | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: KF Teuta Durrës | ||||
| 1st(1st leg) | KF Bylis Ballsh | - | Luftëtari Gjirokastër | 2:1 (2:0) | ||
| 2nd (2nd leg) | Luftëtari Gjirokastër | - | KF Bylis Ballsh | 3:0 dec. | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: Luftëtari Gjirokastër | ||||
| 1st(1st leg) | KF Lushnja | - | KF Laçi | 1:3 (0:2) | ||
| 2nd (2nd leg) | KF Laçi | - | KF Lushnja | 0:1 (0:0) | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: KF Laçi | ||||
| 1st(1st leg) | Turbina Cërrik | - | Flamurtari Vlorë | 1:6 (0:3) | ||
| 2nd (2nd leg) | Flamurtari Vlorë | - | Turbina Cërrik | 5:2 (2:1) | ||
| 1st(1st leg): 29/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: Flamurtari Vlorë | ||||
| 1st(1st leg) | KF Tiranë | - | FK Vllaznia | 2:0 (0:0) | ||
| 2nd (2nd leg) | FK Vllaznia | - | KF Tiranë | 1:0 (0:0) | ||
| 1st(1st leg): 29/11/2017 17:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: KF Tiranë | ||||
| 1st(1st leg) | KS Pogradeci | - | FK Partizani | 0:1 (0:0) | ||
| 2nd (2nd leg) | FK Partizani | - | KS Pogradeci | 3:0 (0:0) | ||
| 1st(1st leg): 30/11/2017 13:00 | 2nd (2nd leg): 13/12/2017 12:00 | Winner: FK Partizani | ||||
