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| 1st(1st leg) | Cobresal | - | Universidad de Chile | 2:4 | ||
| 2nd (2nd leg) | Universidad de Chile | - | Cobresal | 2:1 | ||
| 1st(1st leg): 01/12/2007 20:00 | 2nd (2nd leg): 09/12/2007 22:00 | Winner: Universidad de Chile | ||||
| 1st(1st leg) | O'Higgins | - | Colo-Colo | 0:5 | ||
| 2nd (2nd leg) | Colo-Colo | - | O'Higgins | 1:1 | ||
| 1st(1st leg): 02/12/2007 15:00 | 2nd (2nd leg): 08/12/2007 21:30 | Winner: Colo-Colo | ||||
| 1st(1st leg) | Cobreloa | - | Audax Italiano | 2:2 | ||
| 2nd (2nd leg) | Audax Italiano | - | Cobreloa | 1:0 | ||
| 1st(1st leg): 02/12/2007 20:00 | 2nd (2nd leg): 08/12/2007 19:00 | Winner: Audax Italiano | ||||
| 1st(1st leg) | Universidad Católica | - | Universidad de Concepción | 5:3 | ||
| 2nd (2nd leg) | Universidad de Concepción | - | Universidad Católica | 2:0 | ||
| 1st(1st leg): 02/12/2007 22:30 | 2nd (2nd leg): 09/12/2007 00:00 | Winner: Universidad de Concepción | ||||
